Diagnosis of IgE-mediated allergy in the upper respiratory tract.

A statistical analysis was made of data concerning diagnosis of IgE-mediated allergy in the upper respiratory tract in 292 patients. A study was made of: skin test, total and specific IgE (RAST), X-sinus, red blood investigation, and cytology of nasal smear. It appears that screening for the presence of an IgE-mediated allergy in the upper respiratory tract can be performed efficiently with a limited number of skin tests (rye grass, timothy, birch, house dust mite and cat).

The influence of the Le Fort I osteotomy on nasal airway resistance.

Pre- and postoperative rhinomanometric measurements were done on 13 patients by whom a Le Fort I osteotomy was performed. The claim that Le Fort I osteotomies may produce deleterious respiratory effects in the form of an increase in nasal airway resistance was investigated. The results are discussed.

Beneficial effects of the thymic hormone preparation thymostimulin in patients with defects in cell-mediated immunity and chronic purulent rhinosinusitis. A double-blind cross-over trial on improvements in monocyte polarization and clinical effects.

Twenty patients with chronic purulent rhinosinusitis were treated with TP-1 (Serono; 1 mg/kg body weight), in a double-blind cross-over trial. TP-1 was administered by daily i.m.

[The diagnosis of IgE-mediated allergy of the upper airways].

A statistical analysis was made of data concerning diagnosis of IgE-mediated allergy in the upper respiratory tract in 292 patients. It appears that screening for an IgE-mediated allergy can be performed with a limited number of skin tests (rye grass, timothy, birch, house dust mite and cat). In this study a larger number of skin tests (15 instead of 5) and investigation of specific IgE (RAST) yielded little additional information (in 2% and 3% of the patients, respectively).