Publications by authors named "J A Helms"
Article Synopsis
- The success of dental implants relies on the formation of soft tissues that create a protective barrier against pathogens.
- Researchers studied how anodized surface modifications affect the integration of mucosal tissues in miniaturized implants placed in mice.
- Findings revealed that while soft tissue around implants matures slowly compared to bone, anodized surfaces show some temporary benefits, highlighting the need for strategies to enhance the speed of soft-tissue maturation for better clinical outcomes.
Biomechanical Basis for Bone Healing and Osseointegration of Implants in Sinus Grafts.
Clin Implant Dent Relat Res
December 2024
Article Synopsis
- A deep understanding of how new bone forms and integrates with implants following maxillary sinus floor elevation is essential for improving treatment outcomes and aligning practices with biological principles.
- The effectiveness of sinus lift procedures depends on generating enough viable bone to support implants; however, the minimum amount of vital bone required for success is still debated.
- Factors affecting bone integration include the anatomy of the sinus, individual patient characteristics, and the choice of graft material, suggesting that personalized treatment strategies can improve the predictability and longevity of implant procedures.
Objective: To quantitatively assess the impact of early versus late surgical intervention on midfacial growth using a mouse model.
Methods: A full-thickness mucoperiosteal flap surgery was performed on newborn (P17) mice and on neonatal (P30) mice. High-resolution micro-computed tomographic imaging coupled with histomorphometric analyses was used to assess craniomaxillofacial growth.
In sepsis, inflammation, and nutrient deficiencies endanger cellular homeostasis and survival. Autophagy is primarily a mechanism of cellular survival under fasting conditions. However, autophagy-dependent cell death, known as autophagic cell death, is proinflammatory and can exacerbate sepsis.
View Article and Find Full Text PDFBackground: In the fall of 2020, the COVID-19 infodemic began to affect public confidence in and demand for COVID-19 vaccines in the United States. While polls indicated what consumers felt regarding COVID-19 vaccines, they did not provide an understanding of why they felt that way or the social and informational influences that factored into vaccine confidence and uptake. It was essential for us to better understand how information ecosystems were affecting the confidence in and demand for COVID-19 vaccines in the United States.
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