Publications by authors named "J A Garzon-Tiznado"
Stem-Loop Structures in Iron-Regulated mRNAs of .
Int J Environ Res Public Health
February 2023
is a significant cause of waterborne and foodborne infections, day-care center outbreaks, and traveler's diarrhea worldwide. In protozoa such as and iron affects the growth, pathogenicity mechanisms, and expression of virulence genes. One of the proposed iron regulatory mechanisms is at the post-transcriptional level through an IRE/IRP-like (iron responsive element/iron regulatory protein) system.
View Article and Find Full Text PDFAlcalase hydrolyzates were prepared from the albumin (AH) and globulin (GH) fractions of eight chickpea (Cicer arietinum L.) genotypes from Mexico and 10 from other countries. Protein content, antioxidant activity (AA) (ABTS, DPPH), and degree of hydrolysis were evaluated and the best genotype was selected by principal component analysis.
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- SARS-CoV-2, the virus causing COVID-19, has caused a global pandemic since March 2020 and has three lineages, two of which are present in Mexico.
- Mutations in the spike protein of SARS-CoV-2 (H49Y, D614G, T573I) were studied to see how they affect the protein's structure and its interaction with inhibitors like cepharanthine, nelfinavir, and hydroxychloroquine.
- Molecular simulations indicated that these mutations significantly change the spike protein's behavior and its binding efficiency with the inhibitors, suggesting the need for further experimental research to assess potential clinical implications.
is native to Mexico and its methanol extract (ME) shows relevant biological activities for human health, including the α-glucosidase inhibitory (αGI) activity that suggests its antidiabetic potential. Fractionation of the ME based on the αGI activity (IC in µg/mL) showed that quercetin-3--β-glucoside (131.1), isorhamnetin-3--β-glucoside (166.
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