Publications by authors named "J A Garcia-Merino"

Article Synopsis
  • - The study investigates how cocoa polyphenol extract (CPE) affects myogenic differentiation in C2C12 murine myoblasts exposed to hydrogen peroxide (HO), showing that HO reduces cell viability and damages mitochondria.
  • - Treatment with CPE prior to HO exposure helps protect myoblasts from oxidative damage, improves the number and function of mitochondria, and supports better cell survival and differentiation over time.
  • - Results suggest that CPE supplementation not only preserves mitochondrial health but also aids in maintaining the ability of damaged myoblasts to differentiate, highlighting potential benefits for nutritional interventions.
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Background: People with secondary progressive multiple sclerosis (pwSPMS) experience increasing disability, which impacts negatively on their health-related quality of life (HRQoL). Our aims were to assess the impact of secondary progressive multiple sclerosis (SPMS) on functional status and HRQoL and describe the clinical profile in this population.

Methods: DISCOVER is an observational, cross-sectional, multicenter study with retrospective data collection in real-world clinical practice in Spain.

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Background And Objectives: The complement system is known to play a role in multiple sclerosis (MS) pathogenesis. However, its contribution to disease progression remains elusive. The study investigated the role of the complement system in disability progression of patients with primary progressive MS (PPMS).

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The fabrication of sponge-like vanadium pentoxide (VO) nanostructures using vertically aligned carbon nanotubes (VACNTs) as a template is presented. The VACNTs were grown on silicon substrates by chemical vapor deposition using the Fe/Al bilayer catalyst approach. The VO nanostructures were obtained from the thermal oxidation of metallic vanadium deposited on the VACNTs.

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Tourism in a post-pandemic era will likely be oriented toward nature because contact with nature has restorative health benefits. The purpose of this study was to analyze the antecedents of tourists' intentions to visit nature-based resorts during a pandemic. A nationally representative sample of the Spanish population (n = 500) was recruited by an online commercial panel to test and empirically validate the proposed conceptual framework.

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