Publications by authors named "J A Garcia-Campos"
Rheumatoid arthritis causes progressive joint destruction in the long term, causing a deterioration of the foot and ankle. A clinical practice guideline has been created with the main objective of providing recommendations in the field of podiatry for the conservative management of rheumatoid arthritis. Thus, healthcare professionals involved in foot care of adults with rheumatoid arthritis will be able to follow practical recommendations.
View Article and Find Full Text PDFEnhancing Evidence-Based Practice Competence and Professional Skills Using Infographics as a Pedagogical Strategy in Health Science Students: Insights from the InfoHealth Project.
Eur J Investig Health Psychol Educ
April 2024
Infographics have been recognised as effective visual tools for concise and accessible communication of data and information in various higher education disciplines, particularly in medical education. However, there is a lack of research on their impact on professional skills, difficulty levels, motivation, and overall satisfaction in health science students. Thus, the present study aimed to analyse the knowledge and usage of graphical resources among health science students and evaluate their competencies, the level of challenge they encountered, and their motivation and satisfaction after completing an infographic creation activity.
View Article and Find Full Text PDFObjectives: The aim of this review was to identify the potential intrinsic and extrinsic risk factors (RFs), associated factors (AFs) and consequences of developing calcaneal apophysitis (CA).
Design: Systematic review.
Data Sources: Cochrane Library, Embase, Medline Ovid, PubMed, Web of Science and Evidence, searched from inception to April 2021.
The main objective of the present study was to determine the relationship between kinesiophobia and pain (general and foot pain), foot function, and disease activity in patients with rheumatoid arthritis (RA). A total of 124 interviews were carried out with participants with RA. Participants were recruited from the Hospital Universitario Virgen de las Nieves de Granada in Spain.
View Article and Find Full Text PDFA multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Sci Immunol
January 2023
Article Synopsis
- - Researchers discovered a recurrent mutation in the IRF4 gene, identified as p.T95R, linked to an autosomal dominant combined immunodeficiency (CID) in seven patients from six different families, leading to severe vulnerability to opportunistic infections and low antibody levels.
- - The mutation caused significant defects in the maturation of B cells and alterations in T cell populations, resulting in impaired immune responses, as demonstrated in both human patients and a knock-in mouse model with similar symptoms.
- - The altered IRF4 protein exhibited unusual behaviors, including stronger DNA binding but reduced activity on typical target genes, while also activating noncanonical genes, showcasing a complex interaction that disrupts normal immune function and leads to disease.