Publications by authors named "J A Dvorak"
Impact of the type of vaginal assisted delivery on the pelvic floor and OASI - Ultrasound study.
Eur J Obstet Gynecol Reprod Biol
December 2024
Objective: To assess the prevalence of pelvic floor and anal sphincter trauma in women after assisted vaginal delivery.
Methods: Retrospective study on 201 primiparous women after assisted vaginal delivery, control group 43 women after normal vaginal delivery. 4D translabial ultrasound examination of the levator ani and the anal sphincter was performed according to standard methodology at least 3 months postpartum.
Penile squamous cell carcinoma (pSCC) represents an uncommon malignancy characterized by stagnant mortality, psychosexual distress, and a highly variable prognosis. Currently, the WHO distinguishes between human papillomavirus (HPV) related and HPV independent pSCC. Recently, there has been an evolving line of research documenting the enrichment of HPV-independent pSCC with a high tumor mutational burden (TMB) and programmed death ligand-1 (PD-L1) expression, as well as clusters of genes associated with HPV status.
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- - Uterine sarcomas with KAT6B/A::KANSL1 fusion are a new type of tumor that show a mix of traits from low-grade endometrial stromal sarcomas and smooth muscle tumors, which can confuse initial diagnoses.
- - A study involving 9 such cases found common features like expression of smooth muscle and endometrial stromal markers, as well as the presence of the KAT6B/A::KANSL1 fusion in all tumors.
- - Despite their bland appearance, these tumors can be aggressive, with some patients experiencing severe outcomes, underscoring the need for accurate recognition and diagnosis for better treatment approaches.
Introduction: Burn patients require complex longitudinal care guided by a team with specific clinical expertise. Burn patients are at increased need for readmission, which may result in Fragmentation of care (readmission to hospitals other than the index hospital), that can lead to increases in mortality, length of stay, and financial burden. In the already-complex burn patient, negative effects of care fragmentation may be magnified.
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- Schistosoma mansoni, a parasite introduced to the Americas during the slave trade, poses a significant health issue in South America and the Caribbean; this study analyzes three strains from Liberia, Belo Horizonte, and Puerto Rico, revealing notable differences in virulence and interactions with hosts.* -
- Researchers examined the physical characteristics and immunological effects of these strains on laboratory mice, finding variations in worm shape, egg size, and organ damage, with the Puerto Rican strain showing the highest virulence.* -
- The findings highlight the need for tailored public health strategies and treatments based on the varying behaviors and immune responses of S. mansoni strains, offering valuable insights for controlling schistosomiasis in different regions.*