Publications by authors named "J A Dudler"
Candida spp is responsible for 70-90% of invasive fungal infections. Invasive candidiasis is usually diagnosed by blood culture; other microbiological methods such as PCR, beta-D-glucans and mannans/anti-mannans are available in addition to clinical scores such as the Candida score. Management includes antifungal therapy, removal of catheters and source control, follow-up blood cultures and fundus examination, one possible complication being endophthalmitis.
View Article and Find Full Text PDF[Community-acquired Bacteremia: when should endocarditis be suspected?].
Rev Med Suisse
October 2024
Article Synopsis
- * It highlights that community-acquired bacteremia poses a greater IE risk compared to bacteremia acquired in hospitals, and that certain factors like having implantable cardiovascular devices or a history of IE increase this risk.
- * The article also mentions the development of risk stratification systems to help doctors decide when to perform echocardiography for patients with specific bacteria like S. aureus, and proposes an evaluation algorithm based on these systems.
No standardised and universal treatment is available for antisynthetase syndrome. In particular, there is an unmet need for a single efficient treatment acting on its various manifestations, including interstitial lung disease, myositis and polyarthritis.We describe the cases of two patients with multiple and severe manifestations, including joint, muscular and lung involvement, both refractory to various treatments, including rituximab, who demonstrated significant improvement of all their manifestations, including joint, muscular and lung diseases on tocilizumab.
View Article and Find Full Text PDFRecently, serious infections related to the use of tofacitinib (TOF) for treatment of rheumatoid arthritis (RA) have raised considerable interest. This study aimed to compare the risk for serious infections in patients with RA upon receiving TOF versus biologic disease-modifying antirheumatic drugs (bDMARDs) by age at treatment initiation. We identified adult RA patients exposed to TOF or bDMARDs using data collected by the Swiss registry for inflammatory rheumatic diseases (SCQM) from 2015 to 2018.
View Article and Find Full Text PDFBackground: Postgraduate rheumatology training programmes are already established at a national level in most European countries. However, previous work has highlighted a substantial level of heterogeneity in the organisation and, in part, content of programmes.
Objective: To define competences and standards of knowledge, skills and professional behaviours required for the training of rheumatologists.