Reliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study.

Background And Purpose: The central vein sign (CVS) is a diagnostic imaging biomarker for multiple sclerosis (MS). FLAIR* is a combined MRI contrast that provides high conspicuity for CVS at 3 Tesla (3T), enabling its sensitive and accurate detection in clinical settings. This study evaluated whether CVS conspicuity of 3T FLAIR* is reliable across imaging sites and MRI vendors and whether gadolinium (Gd) contrast increases CVS conspicuity.

Enhanced detection of glutamate via transverse relaxation encoding with narrowband decoupling in the human brain.

Purpose: This study aims to improve the detection of glutamate (Glu) concentration and T using an enhanced transverse relaxation encoding with narrowband decoupling (TREND) technique.

Methods: A new editing pulse was designed to simultaneously invert both Glu H3 spins (2.12 ppm and 2.

In vivo GABA detection by single-pulse editing with one shot.

Purpose: Two-shot γ-aminobutyric acid (GABA) difference editing techniques have been used widely to detect the GABA H4 resonance at 3.01 ppm. Here, we introduce a single-shot method for detecting the full GABA H2 resonance signal, which avoids contamination from the coedited M macromolecules.

Incorporation of the central vein sign into the McDonald criteria.

Background: Diagnosis of multiple sclerosis (MS) frequently relies on MRI dissemination in time (DIT) and space (DIS), as codified in 2017 McDonald criteria (McD 2017). The central vein sign (CVS) is a proposed MS diagnostic biomarker, but its optimal incorporation into McD 2017 has not been extensively studied.

Objective: Evaluate the diagnostic performance of several methods incorporating CVS into McD 2017 radiological DIS criteria.

Characteristics associated with fruit and vegetable consumption in mid aged and older Chinese men and women: a cross-sectional analysis of the first wave of WHO SAGE China.

Adequate fruit and vegetable consumption is essential for healthy ageing and prevention and management of chronic disease. This study aimed to examine characteristics associated with fruit and vegetable consumption in Chinese men and women aged 50 years and over. Data from the first wave of the Chinese cohort (2008-2010) of the WHO's Study on global AGEing and adult health (SAGE) survey was used.