Publications by authors named "J A Davison"
A toddler presented to audiovestibular medicine with mild bilateral, sensorineural hearing loss identified via the Newborn Hearing Screening Programme. This report focuses on the early clinical assessment and aetiological investigation which prompted testing for metabolic disease and highlights the parents' perspective. Early investigation led to a relatively early diagnosis of mucopolysaccharidosis (MPS) type IIIA: Sanfilippo disease which enabled the family to access a novel treatment option which otherwise would not have been possible.
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- * Twenty-eight parents participated in an online survey, revealing skills in cooking and preparation, awareness of health benefits, and knowledge of dietary guidelines as key enablers, while time, financial constraints, and child preferences posed major barriers.
- * Findings suggest that effective interventions should focus on improving parental beliefs and skills regarding healthy eating and increasing knowledge about the benefits of fruits and vegetables to support their children's dietary habits.
Increasing extreme climatic events threaten the functioning of terrestrial ecosystems. Because soil microbes govern key biogeochemical processes, understanding their response to climate extremes is crucial in predicting the consequences for ecosystem functioning. Here we subjected soils from 30 grasslands across Europe to four contrasting extreme climatic events under common controlled conditions (drought, flood, freezing and heat), and compared the response of soil microbial communities and their functioning with those of undisturbed soils.
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- In three clinical trials involving 142 participants with Pompe disease, 17 were deemed suitable for home infusion of avalglucosidase alfa, receiving a total of 419 supervised infusions.
- The majority of participants with late-onset Pompe disease (LOPD) experienced non-serious adverse events, while those with infantile-onset Pompe disease (IOPD) did not report any adverse effects.
- The safety and adverse event rates during home infusion were comparable to those during clinic infusions, indicating that home administration is feasible and safe for stable patients with a prior good infusion history.
Whole food diets in zoos have the potential to reduce microbial contamination and keeper preparation time, whilst also reducing food nutrient breakdown. Given these benefits, it is important to determine whether there is any value in chopping up food. Lemurs (Family Lemuridae) are common in zoos, with over 7500 individuals housed globally.
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