Publications by authors named "J A Child"

Frontloading home care visits has been found to be effective in the nursing profession but has not been investigated in physical therapy (PT) practice. This study aimed to examine the impact of frontloading home PT visits on function in persons with heart failure (HF). This was a prospective multi-center randomized controlled trial with blinded raters.

View Article and Find Full Text PDF

Background And Objectives: The introduction of multiplex gastrointestinal panels at our institution resulted in increased Clostridioides difficile (C. difficile) detection and stool test utilization. We aimed to reduce hospital-onset C.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates the body composition and metabolic health of 25 adults with Silver-Russell syndrome (SRS), a condition linked to low birth weight and potential future health issues.* -
  • Findings reveal that adults with SRS had significantly higher fat percentages, lower lean mass percentages, and reduced bone mineral density compared to unaffected individuals.* -
  • The results indicate that individuals with SRS are at an increased risk for cardiometabolic diseases, highlighting the importance of ongoing health monitoring for this population.*
View Article and Find Full Text PDF

Signal recognition particle (SRP) pathway function in protein translocation across the endoplasmic reticulum (ER) is well established; its role in RNA localization to the ER remains, however, unclear. In current models, mRNAs undergo translation- and SRP-dependent trafficking to the ER, with ER localization mediated via interactions between SRP-bound translating ribosomes and the ER-resident SRP receptor (SR), a heterodimeric complex comprising SRA, the SRP-binding subunit, and SRB, an integral membrane ER protein. To study SRP pathway function in RNA localization, SR knockout (KO) mammalian cell lines were generated and the consequences of SR KO on steady-state and dynamic mRNA localization examined.

View Article and Find Full Text PDF

Background: Expanding the primary care workforce to alleviate general practitioner (GP) workload, improve access and improve quality of care is a current UK strategy. Evidence suggests dietitians can improve patient outcomes and make cost savings. The present study aimed to evaluate a dietitian working as an expert generalist and first contact practitioner (FCP) in a general practice multi-disciplinary team (MDT) to provide appropriate care to patients and reduce GP workload.

View Article and Find Full Text PDF