Assessing Predictive Value of SARS-CoV-2 Epitope-Specific CD8 T-Cell Response in Patients with Severe Symptoms.

Specific T cell responses against SARS-CoV-2 provided an overview of acquired immunity during the pandemic. Anti-SARS-CoV-2 immunity determines the severity of acute illness, but also might be related to the possible persistence of symptoms (long COVID). We retrospectively analyzed ex vivo longitudinal CD8 T cell responses in 26 COVID-19 patients diagnosed with severe disease, initially (1 month) and long-term (10 months), and in a cohort of 32 vaccinated healthcare workers without previous SARS-CoV-2 infection.

Carotid web: the challenging diagnosis of an under-recognized entity.

Background: Determining the cause of acute ischemic stroke is crucial for patient management, particularly for preventing future stroke. In recent years, carotid web (CW), a non-atherosclerotic disorder of the carotid wall, has been found to be an underestimated source of cerebral emboli.

Objective: The present study aimed to analyze the clinical, radiological, and pathological findings, along with the treatments performed in patients with CW and ipsilateral ischemic events.

Postbariatric Surgery Hyperammonemia: A Rare Cause of Encephalopathy.

Hyperammonemic encephalopathy is an under-recognized and potentially fatal complication of Roux-en-Y gastric bypass surgery. We present a case of a 42-year-old woman with no known history of liver disease who experienced worsening encephalopathy 1 year after bariatric surgery. She presented with elevated ammonia and severe encephalopathy requiring intubation.

Peripheral venous bicarbonate levels as a marker of predicting severity in acute pancreatitis: a retrospective study.

Introduction: Acute pancreatitis is an inflammatory process of the pancreas, which can range from mild, self-limited disease to severe disease potentially resulting in death. Although overall mortality has decreased, the incidence of acute pancreatitis is increasing. Severe episodes of acute pancreatitis are more likely to result in prolonged hospitalisation and increased mortality.

Microwire strategy for the endovascular treatment of an aneurysm at the origin of the posterior inferior cerebellar artery.

The ultimate goal of endovascular treatment of intracranial aneurysms is complete occlusion of the aneurysm without compromising the parent artery. Several techniques have been described for the treatment of wide-necked aneurysms. An innovative method is proposed for the treatment of wide-necked aneurysms with the neck incorporated in the parent artery.