Publications by authors named "J A Canas"
Basophil Activation Test: An Additional Diagnostic Tool in Vitamin B12 Allergy.
J Investig Allergol Clin Immunol
February 2025
Article Synopsis
- The study looks at trends and outcomes of parathyroid autotransplantation (PTAT) in children undergoing total thyroidectomy, analyzing data from a surgical database.
- Of the 2,444 patients analyzed, a small percentage underwent PTAT, with the procedure being performed more frequently by adult subspecialists and in cases with more extensive lymph node removal.
- The overall use of PTAT declined over the study period, and no significant differences in early postoperative complications or hospital stays were noted between those who had PTAT and those who did not.
Asthma is a chronic inflammatory lung disease with high prevalence, making it one of the most common chronic conditions worldwide. Its pathophysiology is influenced by a range of genetic and environmental factors, resulting in a complex and heterogeneous disease profile. Asthma is primarily associated with a type 2 (T2) immune response, though non-T2 endotypes also contribute to disease pathology.
View Article and Find Full Text PDFDissolving microneedle array patches (DMAP) enable efficient and painless delivery of therapeutic molecules across the stratum corneum and into the upper layers of the skin. Furthermore, this delivery strategy can be combined with the sustained release of nanoparticles to enhance the therapeutic potential in a wide variety of pathological scenarios. Among the different types of nanoparticles that can be included in microneedle formulations, mesoporous silica nanoparticles (MSN) of tunable pore sizes constitute a promising tool as drug delivery systems for cargos of a wide range of molecular weights.
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