Total aortic arch replacement versus proximal aortic repair for acute type a aortic dissection: A single-center 30-year experience.

Objective: Optimal surgical management of the aortic arch for acute type A aortic dissection remains contentious. We assessed clinical outcomes after total arch replacement and proximal aortic repair (ascending aortic ± hemiarch replacement) for acute type A aortic dissection.

Methods: All patients surgically treated for acute type A aortic dissection at our institution between 1992 and 2021 were included.

Prenatal PFAS exposures and cardiometabolic health in middle childhood in the MIREC cohort.

Studies on prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and cardiometabolic health in childhood have produced inconsistent results. In this study, we evaluated associations between prenatal PFAS exposures, individually and as a mixture, and cardiometabolic outcomes including insulin resistance, beta cell function, blood lipids, blood pressure and central adiposity during middle childhood (7-9 years of age) in a Canadian maternal-child cohort (n = 281). We also explored effect measure modification based on child sex and physical activity.

Enzymatic therapy video-assisted thoracoscopic surgery for pleural infections: a systematic review and meta-analysis.

Aims: Parapneumonic pleural infections are frequently encountered, but the optimal treatment regimen remains controversial. The aim of this systematic review was to investigate whether immediate video-assisted thoracoscopic surgery (VATS) has advantages over intrapleural enzymatic therapy (IET).

Methods: We searched MEDLINE, Embase and Web of Science Core Collection till November 2023 and included studies comparing IET and VATS in adult patients with parapneumonic pleural infections.

Gestational PBDE concentrations and executive function in adolescents with self- and caregiver-report: The HOME study.

Background: Polybrominated diphenyl ethers (PBDEs), synthetic chemicals previously used as flame retardants in commercial products, impact human behaviors, mood symptoms and cognitive abilities.

Objective: We estimated the association of gestational PBDE serum concentrations with early adolescent self- and caregiver-reported ratings of executive function in a prospective pregnancy and birth cohort.

Methods: We measured gestational serum concentrations of five PBDE congeners and created a summary exposure variable (∑BDE: 28, -47, -99, -100 and -153).

Prevalence and associations of kinesiophobia with patient-reported outcomes and mobility measures in axial spondyloarthritis.

Objective: To investigate prevalence and associations of kinesiophobia on patients with axSpA, and its relation to global functioning and health, disease activity, function, spinal mobility and physical activity in comparison to healthy controls (HC).

Methods: Cross-sectional, observational study in which consecutive axSpA-patients with axSpA (n=100) and 20 healthy controls (HC) were examined by the Tampa scale of kinesiophobia (TSK), and the Fear avoidance belief questionnaire (FABQ). Patient reported outcomes and objective assessments of disease activity physical function, global health and functioning as well as the BASMI, the AS physical performance index (ASPI), the Short Physical Performance Battery (SPPB) and Epionics SPINE (ES) measurements, including range of motion (RoM) and kinematics (RoK) were collected.