Publications by authors named "J A Blais"

Many forms of online political incivility threaten democratic norms, contribute to polarization, and are often directed at women and racial minorities. Recent research shows that online political incivility may come from a minority of users that are just as hostile offline as they are online, meaning that individual differences in personality traits may be an important predictor of online political incivility. Drawing upon a large sample of adults living in Canada = 1725), we examined the association between personality traits and online political incivility using robust measures of psychopathy, narcissism, Machiavellianism, and the general traits of the HEXACO.

View Article and Find Full Text PDF

Anthropogenic activities impacting marine environments are internationally recognized as welfare issues for wild cetaceans. This study validates a first evidence-based physical indicator for the welfare assessment protocol of humpback (n = 50) and fin whales (n = 50) living in a highly anthropized environment. Visual assessments of body condition, skin health, prevalence of injuries and parasite/epibiont loads were performed using a species-specific multi-scale measuring tool.

View Article and Find Full Text PDF

Background: Non-adherence to lipid-lowering agents poses significant risks to patients and diminishes treatment effectiveness. Current understanding of patients' preferences regarding the characteristics of these agents is limited. This study aims to qualitatively identify the barriers to lipid-lowering medication adherence and the factors considered by patients with hypercholesterolemia when choosing lipid-lowering agents, and to inform the design of a medication preference study.

View Article and Find Full Text PDF

New antimalarial combination therapies with novel modes of action are required to counter the emergence and spread of drug resistance against existing therapeutics. Here, we present a study to evaluate the preventive activity of a combination of clinical antimalarial drug candidates, cabamiquine and ganaplacide, that have multistage activity against the liver and blood stages of infection. Cabamiquine (DDD107498, M5717) inhibits parasite protein synthesis, and ganaplacide (KAF156) inhibits protein trafficking, blocks the establishment of new permeation pathways, and causes endoplasmic reticulum expansion.

View Article and Find Full Text PDF

Tunable laser photodissociation spectroscopy and photofragment imaging experiments are employed to investigate the spectroscopy and dissociation dynamics of the Mg(benzene) ion-molecule complex. When excited with ultraviolet radiation, Mg(benzene) photodissociates efficiently, producing both Mg and benzene fragments, with branching ratios depending on the wavelength. The wavelength dependence of these processes are similar, with intense resonances at 330 and 241 nm and weaker features at 290 and 258 nm.

View Article and Find Full Text PDF