Association Between Serum MicroRNAs and Abdominal Aortic Aneurysm Diagnosis and Growth.

Objective: This study aimed to examine the association between serum microRNAs (miRNAs) and diagnosis and growth of abdominal aortic aneurysm (AAA), and to test their diagnostic and prognostic value.

Methods: The expression levels of 800 miRNA tags were assessed in 108 patients with AAA, 12 age and sex matched healthy controls (HCs), and 12 patients with peripheral artery disease (PAD) using NanoString technology. Findings were assessed in an independent sample of 66 patients with AAA and 29 age and sex matched HCs by reverse transcriptase polymerase chain reaction.

Diagnosis and Management of a Chronic Lower-Limb Wound in a Patient with Felty Syndrome.

The authors report the case of a 55-year-old patient with a chronic lower-limb wound thought to be secondary to vasculitis. This case illustrates the importance of maintaining a high index of suspicion for vasculitic ulcers in patients with autoimmune disease. Management considerations in this context are also discussed.

Ruptured Left Gastric Artery Aneurysm Associated with Fibromuscular Dysplasia.

Fibromuscular dysplasia is a non-inflammatory, non-atherosclerotic vascular disease that commonly affects renal and carotid arteries but involvement of virtually any vascular territory has been observed. This is a case report of a ruptured left gastric artery aneurysm as the first presentation of fibromuscular dysplasia. After written consent from the patient, relevant clinical notes and imaging were retrospectively reviewed and critically analysed.