Assessing differential personal information value with social discounting and hypothetical payment tasks with university students.

Different personal information types are shared at different rates during a social-discounting task. However, it is unclear whether differences in social-discounting rates between different personal information types are related to differences in valuing personal information. To assess the value of personal information more directly, 160 university student participants completed four hypothetical purchase tasks (HPT) for protecting identification, health, security, and financial personal information at 17 ascending price points and a social-discounting task for one of those four different personal information types.

IRF5 Controls Plasma Cell Generation and Antibody Production via Distinct Mechanisms Depending on the Antigenic Trigger.

Elevated levels of serum autoantibodies are a hallmark of systemic lupus erythematosus (SLE) and are produced by plasma cells in response to a variety of antigenic triggers. In SLE, the triggers are complex and may include both T cell-dependent/-independent and TLR-dependent/-independent mechanisms of immune activation, which ultimately contributes to the significant immune dysregulation seen in patients at the level of cytokine production and cellular activation (B cells, T cells, dendritic cells, neutrophils and macrophages). Interferon regulatory factor 5 (IRF5) has been identified as an autoimmune susceptibility gene and polymorphisms in IRF5 associate with altered expression and hyper-activation in distinct SLE immune cell subsets.

Thermal characterization of vertical interface by scanning photothermal radiometry.

In this work, scanning photothermal radiometry is used for imaging and to characterize a submicron crack. From the thermal images, the evolution of the crack is mapped in the space with micrometer resolution. A vertical contact interface at the steel-steel junction is used to represent a micro-crack with a thickness less than 0.

Atomically Precise Graphene Nanoribbon Transistors with Long-Term Stability and Reliability.

Atomically precise graphene nanoribbons (GNRs) synthesized from the bottom-up exhibit promising electronic properties for high-performance field-effect transistors (FETs). The feasibility of fabricating FETs with GNRs (GNRFETs) has been demonstrated, with ongoing efforts aimed at further improving their performance. However, their long-term stability and reliability remain unexplored, which is as important as their performance for practical applications.

Atopic dermatitis and IgE-mediated food allergy: Common biologic targets for therapy and prevention.

Objective: To highlight common mechanistic targets for the treatment of atopic dermatitis (AD) and IgE-mediated food allergy (IgE-FA) with potential to be effective for both diseases and prevent atopic progression.

Data Sources: Data sources were PubMed searches or National Clinical Trials (NCT)-registered clinical trials related to AD, IgE-FA, and other atopic conditions, especially focused on the pediatric population.

Study Selections: Human seminal studies and/or articles published in the past decade were emphasized with reference to preclinical models when relevant.