Phytochemical Investigation and Biological Studies on Selected Species.

is the more recent name for the genus , which contains over 250 individual species of flowering plants in the family . Several species are used in folk medicine and have been reported to exhibit various biological activities. Although known to exhibit different terpenoids and flavonoids, the chemistry of the genus is not comprehensively studied due to the structural complexity of the compounds.

Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities, Molecular Docking, and Antioxidant Capacities of Constituents.

Shortage in insulin secretion or degradation of produced insulin is the principal characteristic of the metabolic disorder of diabetes mellitus (DM). However, because the current medications for the treatment of DM have many detrimental side effects, it is necessary to develop more effective antidiabetic drugs with minimal side effects. Alpha-glucosidase and alpha-amylase inhibitors are directly implicated in the delay of carbohydrate digestion.

Antimycobacterial, Cytotoxic, and Antioxidant Activities of Abietane Diterpenoids Isolated from .

Medicinal plants of the genus (Lamiaceae) are well known for their ethnomedicinal applications. , which is native to South Africa, is traditionally used in the treatment of respiratory conditions, scabies, and cutaneous wounds. The phytochemical studies of led to the isolation of five known royleanone abietanes, namely, 6β,7α-dihydroxyroyleanone (), 7α-acetoxy-6β-hydroxyroyleanone (), horminone (), coleon U quinone (), and carnosolon ().

Corrigendum to "Antiproliferative and Apoptosis Induction Potential of the Methanolic Leaf Extract of (G. Don)".

[This corrects the article DOI: 10.1155/2015/756482.].

An Insight into the Mechanism of Holamine- and Funtumine-Induced Cell Death in Cancer Cells.

Holamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of . The selective anti-proliferative and cell cycle arrest effects of holamine and funtumine on cancer cells have been previously reported. The present study evaluated the anti-proliferative mechanism of action of these two steroidal alkaloids on cancer cell lines (HT-29, MCF-7 and HeLa) by exploring the mitochondrial depolarization effects, reactive oxygen species (ROS) induction, apoptosis, F-actin perturbation, and inhibition of topoisomerase-I.