Detection of radiosensitive subpopulations with Raman microspectroscopy.

Although significant advances in understanding the molecular drivers of acquired and inherited radiosensitivity have occurred in recent decades, a single analytical method which can detect and classify radiosensitivity remains elusive. Raman microspectroscopy has demonstrated capabilities in the objective classification of various diseases, and more recently in the detection and modelling of radiobiological effect. In this study, Raman spectroscopy is presented as a potential tool for the detection of radiosensitivity subpopulations represented by four lymphoblastoid cell lines derived from individuals with ataxia telangiectasia (2 lines), non-Hodgkins lymphoma, and Turner's syndrome.

Drug Survival of Biological Therapies in Smokers and Non-Smokers With Psoriasis: A Retrospective Cohort Study Using Data From the Australasian Psoriasis Registry.

Background: Smoking is a modifiable risk factor that increases the likelihood of developing psoriasis and the severity of the disease. In recent years, biological therapies have transformed the management of psoriasis. There is conflicting evidence about whether smoking affects the efficacy of biologics.

The 2023 World delirium awareness and quality Survey: A Canadian substudy.

Objective: This study aimed to evaluate the proportion of screened patients with delirium and the strategies used for its management in Canadian hospitals caring for critically ill children or adults.

Methods: This is a secondary analysis of a cross-sectional study completed on World Delirium Awareness Day (March 15, 2023). Respondents completed a 35-question survey on the proportion of screened patients with delirium (at 8:00 am and 8:00 pm), treatment, and management strategies employed.

Psychometric properties of the five-minute speech sample: Measuring parental schemas among caregivers in the child welfare system.

Background: Parental schemas are implicit beliefs parents have about their child that then shape their behaviors and impact child well-being and adjustment. This research evaluates the psychometric properties of the Five-Minute Speech Sample coded with the Family Affective Attitude Rating Scale of the (FMSS-FAARS) to assess parental schemas among caregivers involved in the child welfare system (CWS).

Objective: Evaluate the psychometric properties of the FMSS-FAARS with a large, diverse sample of caregivers involved with the CWS.