Publications by authors named "J A Alonso-Cadenas"
Article Synopsis
- - Spain introduced universal RSV prophylaxis in the 2023-2024 season, allowing all newborns to receive nirsevimab, particularly benefiting infants under 6 months through extended immunization efforts.
- - A study in 15 pediatric emergency departments showed significant decreases in respiratory infections: a 57.7% drop in lower respiratory tract infections and a 63.1% reduction in hospital and PICU admissions related to acute bronchiolitis.
- - The findings indicate that nirsevimab is highly effective in protecting infants from RSV, with extended catch-up immunization yielding the best results, although cost-effectiveness remains a consideration.
Performance of blood enterovirus and parechovirus polymerase chain reaction testing in young febrile infants: a prospective multicentre observational study.
Arch Dis Child
January 2025
Objectives: To analyse the performance of blood enterovirus and parechovirus PCR testing (ev-PCR) for invasive bacterial infection (IBI) (isolation of a single bacterial pathogen in a blood or cerebrospinal fluid culture) when evaluating well-appearing infants ≤90 days of age with fever without a source (FWS).
Methods: We describe the well-appearing infants ≤90 days of age with FWS and normal urine dipstick. We performed a prospective, observational multicentre study at five paediatric emergency departments between October 2020 and September 2023.
Children are highly vulnerable to mild traumatic brain injury (mTBI). Blood biomarkers can help in their management. This study evaluated the performances of biomarkers, in discriminating between children with mTBI who had intracranial injuries (ICIs) on computed tomography (CT+) and (1) patients without ICI (CT-) or (2) both CT- and in-hospital-observation without CT patients.
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