A wearable system for experimental knee pain during real-world locomotion: habituation and motor adaptation.

We developed a novel, wearable system that couples motion sensing and electrical stimulation in real-time to study motor adaptation in new environments. In two experiments we established key information needed in the development of our system including 1) pain habituation patterns and motor adaptations to knee pain while walking, 2) a model of electrical stimulation magnitude as a function of pain perception, and 3) gait-phase-dependent modulation of pain intensity. Over three 10-minute walking bouts, we observed significant pain habituation (p<0.

The Fitness, Rest, and Exercise for Strength and Health (FRESH) Study: A Three-Year Comparison of College Students' Perceived and Measured Health Metrics.

The undergraduate college years are a critical transition period for young adults in establishing life-long health behaviors. : Within the FRESH Study, we aimed to understand the relationship between perceived physical health, perceived mental health, and specific health metrics (e.g.

Estimating whole-body centre of mass sway during quiet standing with inertial measurement units.

Our ability to balance upright provides a stable platform to perform daily activities. Balance deficits associated with various clinical conditions may affect activities of daily living, highlighting the importance of quantifying standing balance in ecological environments. Although typically performed in laboratory settings, the growing availability of low-cost inertial measurement units (IMUs) allows the assessment of balance in the real world.

Seeing the piles of the velvet bending under our finger sliding over a tactile stimulator improves the feeling of the fabric.

Using friction modulation to simulate fabrics with a tactile stimulator (i.e. virtual surface) is not sufficient to render fabric touch and even more so for hairy fabrics.

SARS-CoV-2 spike-based virus-like particles incorporate influenza H1/N1 antigens and induce dual immunity in mice.

A vaccine effective against both SARS-CoV-2 and influenza A (IAV) viruses could represent a cost-effective strategy to reduce their combined public health burden as well as potential complications arising from co-infection. Based on previous findings that full-length SARS-CoV-2 spike (S) expression can induce high-level, enveloped VLP (eVLP) production in CHO cells, we tested whether IAV H1N1 hemagglutinin (H1) and neuraminidase (N1) could also be displayed on these particles. We found that co-incorporation of the IAV surface antigens in spike VLPs (S-VLPs) was highly efficient: upon transient co-expression of S + H1 or S + H1 + N1 in CHO cells, the resulting VLPs contained similar amounts of the SARS-CoV-2 S and IAV antigens.