Publications by authors named "J -F Kuo"

The EZ DEVICE is an integrated fluorescence microflow cytometer designed for automated cell phenotyping and enumeration using artificial intelligence (AI). The platform consists of a laser diode, optical filter, objective lens, CMOS image sensor, and microfluidic chip, enabling automated sample pretreatment, labeling, and detection within a single compact unit. AI algorithms segment and identify objects in images captured by the CMOS sensor at 532 and 586 nm emission wavelengths.

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Objective: The field of endocrine surgery has been expanding its minimally invasive techniques to treat a wide range of thyroid pathologies. Radiofrequency ablation (RFA) is one targeted thermal therapy that has been identified as safe and effective for the treatment of benign pathologies as an alternative to surgery. We have employed RFA at our institution and are reporting our experience with this techniques safety, efficacy, and considerations in the treatment of toxic adenomas and multinodular goiters.

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Article Synopsis
  • - The study developed a nomogram to predict the likelihood of pelvic lymph node metastases (ypN+) after neoadjuvant chemotherapy in nonmetastatic muscle-invasive bladder cancer patients, finding that ypN+ is linked to worse overall survival.
  • - Data from 6,194 patients were analyzed, revealing that 22.8% of high-risk patients had ypN+, compared to only 8.0% in the low-risk group, with high-risk patients experiencing significantly shorter survival (36.1 vs. 74.0 months).
  • - Key factors contributing to the nomogram included age, time from diagnosis to treatment, and the tumor’s histology and stage, making it a valuable tool for assessing risk
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  • The study investigates how well the drop in coronary pressure after administering nitroglycerin (NTG) can predict fractional flow reserve (FFR) compared to the resting full-cycle ratio (RFR).
  • In total, 202 vessels were analyzed from two prospective studies, where NTG-Pd/Pa showed a strong correlation with FFR (r = 0.945) and a cutoff value of 0.85 was established.
  • Results indicated that NTG-Pd/Pa performed better than RFR in predicting FFR ≤ 0.8, with higher accuracy (91% vs. 84%) and sensitivity, making it a potentially more effective diagnostic tool.
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Overactive bladder (OAB) significantly impairs quality of life in the elderly. Although the intradetrusor injection of botulinum toxin type A (BoNT-A) is a treatment option, its effects on older adults remain uncertain. This study aimed to evaluate the efficacy and safety of BoNT-A intradetrusor injections in elderly OAB patients through a systematic review and meta-analysis.

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