Publications by authors named "Izzie Dighero"
Background: Statistical modelling studies based on excess morbidity and mortality are important for understanding RSV disease burden for age groups that are less frequently tested for RSV. We aimed to understand the full age spectrum of RSV morbidity and mortality burden based on statistical modelling studies, as well as the value of modelling studies in RSV disease burden estimation.
Methods: The databases Medline, Embase and Global Health were searched to identify studies published between January 1, 1995, and December 31, 2021, reporting RSV-associated excess hospitalisation or mortality rates of any case definitions using a modelling approach.
Background: Understanding the risk factors for poor outcomes among COVID-19 patients could help identify vulnerable populations who would need prioritisation in prevention and treatment for COVID-19. We aimed to critically appraise and synthesise published evidence on the risk factors for poor outcomes in hospitalised COVID-19 patients.
Methods: We searched PubMed, medRxiv and the WHO COVID-19 literature database for studies that reported characteristics of COVID-19 patients who required hospitalisation.
Article Synopsis
- RSV is the main viral cause of acute lower respiratory infections in children under 5, but there is limited national data on its impact.
- Researchers sought to estimate RSV-related hospitalizations in this age group by analyzing data from 58 countries using two statistical methods.
- The analysis included data from 334 studies, estimating that median annual RSV-associated hospitalizations for children under 5 across various countries reached approximately 8.25 million.