Publications by authors named "Izzati Haizan"
Exosomes, crucial for intercellular communication, hold potential as noninvasive liquid biopsy biomarkers especially in early breast cancer detection benefitted from the distinctive "cancer signature" on their membrane surface. Yet, the present methodologies of exosomes for breast cancer detection have involved the implementation of only a single member from the tetraspanin protein group as a biomarker. Moreso, due to the high concentration of exosomes in complex body fluids, there is a compelling need to measure a small concentration of cancer-derived exosomes with a low background noise signal.
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- The growing aging population necessitates better diagnosis and treatment of neurodegenerative diseases (NDDs), and two-dimensional (2D) materials present significant advantages for this purpose.
- 2D materials enhance the development of biosensors for early NDD detection, targeted drug delivery systems that cross the blood-brain barrier, and support cell growth in tissue engineering to restore neural functions.
- Overall, the use of 2D materials in NDD research holds the potential to improve patient care and quality of life for an increasingly aging demographic.
Article Synopsis
- * LFAs utilize advanced nanomaterial-based optical sensing technologies for quick and effective detection of viral proteins, requiring less training and infrastructure compared to conventional techniques.
- * Despite progress in the development of LFAs, challenges remain in creating systems that are simple, stable, highly sensitive, and selective, with the potential to improve clinical diagnostics and environmental monitoring significantly.
In the context of virus outbreaks, the need for early and accurate diagnosis has become increasingly urgent. In addition to being crucial for effective disease control, timely and precise detection of viral infections is also necessary for the implementation of essential public health measures, especially during pandemics. Among these measures, point-of-care testing (POCT) stands out as a powerful approach with the potential to revolutionize the landscape of viral diagnosis.
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