Hemostatic Antimicrobial Hydrogels Based on Silicon, Iron, Zinc, and Boron Glycerolates for Wound Healing Applications.

The use of glycerolates of biogenic elements as biocompatible precursors in sol-gel synthesis is an innovative direction and opens up new scientific and practical prospects in chemistry and technology of producing practically important biomedical materials, including hemostatic, antimicrobial, and wound healing materials. Using biocompatible precursors, silicon, zinc, boron, and iron glycerolates, new bioactive nanocomposite hydrogels were obtained by the sol-gel method. The composition and structural features of the hydrogels were studied using a complex of modern analytical techniques, including TEM, XRD, AES, and ESI MS.

The Good Compliance is an Opportunity to Avoid Pathological Brain Aging.

Preservation of health, increase in life expectancy determine the need to improve the effectiveness of medical recommendations, which, despite the success of pharmacology, are insufficient for reasons related to the low level of compliance with these recommendations by patients. The authors of the article believe that compliance is a kind of quantifiable and behaviorally realized reflection of therapeutic interaction, refracted through the prism of the patient's individual personality characteristics. Participants of the study-148 employees of medical institutions: 12 men, 136 women, their age ranged from 27 to 74 years.

[Efficacy and safety of anticoagulant treatment for non-valvular atrial fibrillation in multimorbid patients].

Objective: Assessment of the safety and efficacy of anticoagulant treatment in patients with nonvalvular atrial fibrillation (AF) in a multimorbidity setting.

Materials And Methods: The cross-sectional study included 104 patients diagnosed with nonvalvular AF and followed in the medical facilities of Yekaterinburg. The subjects were interviewed, anthropometric measurements were made, and the risk of thromboembolic complications was evaluated using the CHA2DS2-VASc score.

[Detection of distal forearm osteopenia and osteoporosis in Perm women aged 50 years or older].

Aim: to assess the prevalence of subnormal bone mineral density (BMD) of the distal forearm among women living in Perm and the Perm Region, by taking into account the data of distal forearm X-ray densitometry and risk factors of osteoporosis (OP).

Subjects And Materials: This one-stage study included 1765 women aged 50-90 years (mean age 61.8 years, standard deviation 8.

[Quality of life in women with arterial hypertension in the climacteric period].

This study was designed to compare quality of life (QL) in women with arterial hypertension (AH) and with normal arterial pressure in the climacteric period. It included 146 postmenopausal women with AH (age median 57 years). The control group comprised 146 women without AH matched by age and duration of menopause.

[Metabolic syndrome and decreased bone mineral density in climacteric women].

The objective of this work was to evaluate the influence of insulin resistance on the development of syndrome of osteopenia. The case-control study included 124 women with osteopenia and osteoporosis of the distal forearm segment diagnosed by X-ray densitometry in accordance with the WHO criteria (DTX 200). One group of the patients comprised 62 women with metabolic syndrome (MS) by the criteria of NCPE ATP III.

[Frequency of diagnosis of postmenopausal osteoporosis of the spine, distant radius and extravertebral fractures in women with normal body mass, overweight and obesity].

Aim: To assess features and peculiarities of postmenopausal osteoporosis (OP) in women with normal body mass, overweight and obesity.

Material And Methods: Dual energy X-ray absorptiometry of the lumbal spine (Lunar DPX) and distal radius X-ray absorptiometry (DTX 200) were performed during cross-section study of 730 symptomatic postmenopausal women.

Results: OP was diagnosed in 253 (34.

[Postmenopausal osteoporosis in obese women].

Aim: assessment of frequency of obesity and comorbidities in women with postmenopausal osteoporosis (OP).

Methods: cross-sectional study included 243 postmenopausal symptomatic women with OP diagnosed by dual energy lumbar spine absorptiometry.

Results: normal body mass was found in 74 women (30.

[A cross-sectional study of lipid metabolism in postmenopausal women].

Aim: To assess frequency of atherogenic dyslipidemia in postmenopausal residents of Ekateringurg.

Methods: Cross-sectional study included 1100 female patients of outpatient menopausal clinic. All were residents of Ekaterinburg aged from 28 to 64 years.

[The evaluation of cardiovascular risk in postmenopausal women with osteopenia].

The purpose of the study was to evaluate the prevalence of the most important cardiovascular risk factors in postmenopausal women in correlation with bone mineral density (BMD). A hundred and fifty postmenopausal women were included in a case control study. The subjects were distributed into three equal groups: normal bone mass; osteopenia; non-complicated osteoporosis.

[Magnesium deficit in climacteric women].

The aim of the study was to assess the prevalence of magnesium deficit (MD) in climacteric women and its effect on the severity of climacteric syndrome (CS). This cross-sectional study included 165 women with typical CS manifestations. Patients with arterial hypertension were excluded.

[Osteopenia and osteoporosis of the distal forearm in menopausal females].

Aim: To estimate the frequency of decreased bone mineral density (BMD) in the distal forearm of the females visiting a specialized city consultative center for menopausal pathology, by using dual energy X-ray absorptiomentry (DEX4) and to assess risk factors for osteoporosis.

Materials And Methods: The cross-sectional study included 681 females (mean age 54.8 +/- 5.

[Incidence of thyroid and cardiovascular diseases in menopausal females].

The purpose of the study was to estimate the incidence of thyroid dysfunction and cardiovascular diseases in perimenopausal females. The cross-sectional study covered 554 females (mean age 52.6±6.

[Hyperinsulinemia and insulin-resistance in climacteric women with metabolic syndrome].

The purpose of the study was to evaluate the peculiarities of carbohydrate and lipid dysmetabolism in climacteric women with metabolic syndrome (MS). The subjects of this case-control study were 124 women. The main group consisted of 62 women with MS according to A TP III classification; the control group included 62 women without MS.

[Arterial hypertension, disorders of carbohydrate and lipid metabolism in obese perimenopausal females].

Aim: To examine prevalence of arterial hypertension (AH), disorders of carbohydrate and lipid metabolism in females with obesity in perimenopause.

Material And Methods: One-stage trial enrolled 358 obese females in menopause seeking advice in the city center for health and family planning in Ekaterinburg (mean age 50.5 +/- 5.

[Methods of hormone replacement therapy in hypertensive women].

A comparative retrospective study was made to examine influence of replacement therapy by estradiol valeriate and climonorm on perimenopausal hypertension. The test group (25 hypertensive women) received climonorm for 6 months. Control women received hypotensive therapy.

[The significance of variation pulsometry in the diagnosis of ischemic heart disease during mass screening of the population].

The use of computerized heart rhythm assessment in diagnosis of patients at high risk of ischemic heart disease during epidemiological surveys is discussed. The method has been shown to be of value in detection of ischemic heart lesions developing in menopausal women. The method can be used to monitor patients in the course of long-term follow-up.