The use of a woman's own eggs in her first IVF treatment at the age of 48 years and 10 months with successful live birth after PGT-A: a case report.

Natural conception in women after the age of 45 years is rare. The probability of successful pregnancy in this specific group of women after IVF and embryo transfer with autologous oocytes is also reduced. In addition, advanced maternal age is associated with an increased risk of aneuploidies and other associated complications during pregnancy.

Single-Molecule Catalysis in the Palladium Cross-Coupling Reaction Cycle.

Single-molecule (SM) methods are applied to study various types of catalytic processes in chemical and biochemical reactions. In this study, the Suzuki-Miyaura cross-coupling reaction forming a fluorescent product is investigated within the SM approximation. Stochastic analysis of emission intermittency in selected nanoscopic spots allows us to determine the single-molecule turnover frequency (SM-TOF) of the Pd catalyst in a specific probe reaction.

Reactive Phenanthrene Derivatives as Markers of Amino Groups in Fluorescence Microscopy of Surface Modified Micro-Zeolite L.

Two reactive phenanthrene derivatives, 4-(1H phenanthrol [9,10-d] imidazole-2-yl) benzaldehyde (PIB) and 6,9-dimethoxyphenanthro[9,10-c]furan-1,3-dione (PA) with high fluorescent quantum yields were prepared and used as fluorescent marker in fluorescence microscopy. In particular, silane modified μmZeolite-L containing amino group (-NH) in the surface were labeled with the phenanthrene derivatives allowing good imaging resolution and spectroscopy measurements. The presence of a large Stokes shift of the probes due to their intramolecular charge-transfer character gives an advantage of the compounds in confocal laser fluorescence microscopy due to easy signal separation in excitation and emission wavelengths.