The additional prognostic value of myocardial perfusion SPECT in patients with known coronary artery disease with high exercise capacity.

Background: The prognostic value of myocardial perfusion imaging (MPI) in patients with known coronary artery disease (CAD) and high exercise capacity is still unknown. We sought to determine the MPI additional prognostic value over electrocardiography (ECG) stress testing alone in patients with known CAD who achieved ≥ 10 metabolic equivalents (METs).

Methods And Results: We evaluated 926 patients with known CAD referred for MPI with exercise stress.