Publications by authors named "Izabela Roszko"

Unlabelled: Intensity of gastric mucosa and/or duodenal inflammation and their clinical consequences in response to Helicobacter pylori infection depend on a given strain virulence. A receptor protein IceA, induced by contact with epithelium gene A, is one of important proteins in the process of infection. Examinations of iceA genotype have show that the rate of occurrence of H.

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Unlabelled: Bacteria virulent proteins, among other vacA, have a significant role in the occurrence of gastric mucositis.

Aim: The aim of the study was the evaluation of occurrence rate of alleles s1 and s2 of Helicobacter pylori vacA genome in children and adults, inhabitants of the Podlasie province. It was also to determine the correlation between infection with a determined s1 or s2 vacA genotype of the bacterium and the degree of severity and activity of antral mucositis.

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The frequency of Helicobacter pylori infection in population can depend on the organism resistance, genetic condition, and bacterial strains virulence. A vacA gene, of mosaic structure, which encodes vacuolating cytotoxin is one of the known genes of H. pylori.

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The purpose of the study was to assess the incidence of Helicobacter pylori infection in members of families in the Podlasie Region. The study included members of 205 families in whom IgG antibodies against H. pylori were determined.

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In literature and clinical findings, the attention has been turned to the resistance to the antibiotics used in Helicobacter pylori eradication, especially metronidazole and clarithromycin. Drug-resistance was evaluated in 50 children. Primary drug-resistance to the antibiotics used in eradications was determined in this group, and additionally, in 18 children who were subjected twice to unsuccessful eradicative therapy.

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