Analysis of the influence of hormone replacement therapy on TNF-alpha serum levels in menopausal women.

Objective: The aim of the study was to investigate and compare levels of TNF-α in serum of menopausal women treated and not treated with hormone replacement therapy (HRT).

Design: The study was designed to verify whether there is a correlation between the concentrations of this cytokine and bone mineral density (BMD).

Material/methods: The study was carried out on a group of 60 women during menopause - 30 untreated (control group) and 30 treated with HRT (study group).