A Rare Case of Granulomatous Mastitis in the Accessory Axillary Breast of a Pregnant Woman Successfully Treated by Surgery.

Granulomatous mastitis (GM) is a chronic inflammatory disease of the breast that usually occurs in women of reproductive age. However, GM during pregnancy is unusual and only one case of GM in the accessory breast has been reported so far. Here, we report an extremely rare case of GM in the accessory axillary breast of a pregnant woman.

[A Long-Term Survival Case of Liver Metastasis from Remnant Gastric Cancer Treated by CapeOX, S-1, and Surgery].

A 70-year-old man, who had undergone distal gastrectomy for early gastric cancer at 63-year-old, had multiple liver metastases from remnant gastric cancer, which was diagnosed as cT3(SS), N0, M1, cStage Ⅳ. After a regimen consisting of 8 courses of capecitabine plus oxaliplatin and 2 courses of S-1 was administered, clinical CR was confirmed for the remnant gastric cancer and multiple liver metastases. Chemotherapy was administered for 10 months and discontinued for side effects and the needs of the patient.

Regional education on endoscopic surgery using a teleconference system with high-quality video via the internet: Saga surgical videoconferences.

Background: Effective education about endoscopic surgery (ES) is greatly needed for unskilled surgeons, especially at low-volume institutions, to maintain the safety of patients. We have tried to establish the remote educational system using videoconference system through the internet for education about ES to surgeons belonging to affiliate institutions. The aim of this manuscript was to report the potential to establish a comfortable remote educational system and to debate its advantages.

Online Survey of Gambling Participation and Problem Gambling in Chiba City: Problem Gambling Rates May be Strongly Influenced by the Administration Mode.

Prevalence studies on gambling participation and problem gambling in Japan have been limited. To obtain data showing the current status of gambling in Japan, we conducted an online survey on gambling participation and problem gambling among residents in Chiba City. The online data collection was conducted through an Internet research firm.

Pegfilgrastim-associated large-vessel vasculitis developed during adjuvant chemotherapy for breast cancer: A case report and review of the literature.

Introduction: Granulocyte colony-stimulating factor (G-CSF) is widely used as a neutrophil supportive therapy in breast cancer chemotherapy. Common adverse events of G-CSF include bone pain, headache, and fatigue; however, reports of G-CSF-associated vasculitis are few.

Case Report: A 66-year-old woman who had undergone surgery for breast cancer received adjuvant chemotherapy with prophylactic use of pegfilgrastim (peg-G).

Diagnostic Performance of Dual-Layer Computed Tomography for Deep Vein Thrombosis in Indirect Computed Tomography Venography.

Background: The aim of this study was to evaluate the quality and diagnostic performance of virtual monochromatic images (VMI) obtained with dual-layer dual-energy computed tomography (DL-DECT) during indirect CT venography (CTV) for deep vein thrombosis (DVT).

Methods and results: This retrospective study was approved by the Institutional Review Board, which waived the requirement for informed consent. We retrospectively enrolled 45 patients who underwent CTV with DL-DECT, and VMI were retrospectively generated.

Usefulness of Virtual Monochromatic Dual-Layer Computed Tomographic Imaging for Breast Carcinoma.

Objective: This study aimed to evaluate virtual monochromatic images (VMIs) obtained using dual-layer dual-energy computed tomography (CT) for breast carcinoma.

Methods: We retrospectively enrolled 28 patients with breast cancer who were pathologically diagnosed using dual-layer dual-energy CT. Virtual monochromatic images (40-200 keV) were generated.

Impact of hybrid FDG-PET/CT on gross tumor volume definition of cervical esophageal cancer: reducing interobserver variation.

Intensity-modulated radiation therapy is being increasingly used to treat cervical esophageal cancer (CEC); however, delineating the gross tumor volume (GTV) accurately is essential for its successful treatment. The use of computed tomography (CT) images to determine the GTV produces a large degree of interobserver variation. In this study, we evaluated whether the use of [18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET)/CT fused images reduced interobserver variation, compared with CT images alone, to determine the GTV in patients with CEC.

Dual-layer dual-energy computed tomography for the assessment of hypovascular hepatic metastases: impact of closing k-edge on image quality and lesion detectability.

Objectives: To evaluate the image quality of virtual-monoenergetic-imaging (VMI) from dual-layer dual-energy CT (DLCT) for the assessment of hypovascular liver metastases and its effect on lesion detectability.

Methods: Eighty-one patients with hypovascular-liver-metastases undergoing portal-venous-phase abdominal DLCT were included. Polyenergetic-images (PEI) and VMI at 40-200 keV (VMI, 10-keV interval) were reconstructed.

Spiral flow-generating tube for saline chaser improves aortic enhancement in Gd-EOB-DTPA-enhanced hepatic MRI.

Objectives: To evaluate the effect of a spiral tube on contrast enhancement in the hepatic arterial phase (HAP) of gadoxetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI).

Methods: In this retrospective study, we observed 104 patients who underwent dynamic MRI of the liver between October 2017 and December 2017. Three Gd-EOB-DTPA injection protocols were compared: (A) conventional method (undiluted Gd-EOB-DTPA, injection rate 1 ml/s, n = 36); (B) spiral dilution method (1:1 diluted Gd-EOB-DTPA with saline [off-label], injection rate 2 ml/s via spiral tube, n = 38); (C) spiral-flushed method (undiluted Gd-EOB-DTPA, injection rate 1 ml/s via spiral tube, n = 30).

Effect of metal-containing topical agents on surface doses received during external irradiation.

The ability of topical metal-containing agents (MCAs) to enhance radiation dermatitis remains controversial. In the present study, we evaluated increases in surface doses associated with topical agents at different application thicknesses and with MCAs versus non-metal containing agents (NMCAs). We assessed two clinically available MCAs, zinc oxide ointment (ZOO) and silver sulfadiazine cream (SSDC), and eight NMCAs.

Colonic distention and patient acceptance of CT colonography: supine/prone left/right lateral scanning.

Objective: To prospectively evaluate and complete the colonic distention and patient acceptance of CT colonography (CTC) in the supine/prone and left/right lateral positions.

Methods: A total of 220 consecutive patients were alternately allocated to the supine/prone positioning or left/right lateral positioning group. Two readers scored the degree of colonic distention by segment using a 4-point Likert scale (4 = optimal, 3 = adequate, 2 = inadequate, 1 = collapsed).

Emergency radiology after a massive earthquake: clinical perspective.

Earthquakes are unpredictable and inevitable disasters, causing various earthquake-related disorders. Medical imaging, including digital radiography, computed tomography, and magnetic resonance imaging, plays a key role in the evaluation of earthquake-related disorders. We here demonstrate the concept of diagnostic imaging after a massive earthquake and review the common imaging features of various disorders in casualties and evacuees.

The Usefulness of Dual-Layer Spectral Computed Tomography for Myelography: A Case Report and Review of the Literature.

We describe a case of lumbar stenosis in which retrospective spectral analysis using dual-layer spectral detector computed tomography (CT) had the ability to expand the evaluable region in the spinal canal. Spinal canal stenosis is a common condition whose symptoms (such as lower back and leg pain with walking) deteriorate the quality of life. Generally, magnetic resonance imaging (MRI) and CT myelography are performed to diagnose canal stenosis.

Usefulness of a Low Tube Voltage: Knowledge-Based Iterative Model Reconstruction Algorithm for Computed Tomography Venography.

Objectives: The objective of this study was to evaluate the use of 80-kVp scans with knowledge-based iterative model reconstruction (IMR) for computed tomography venography (CTV).

Methods: This prospective study received institutional review board approval; a previous informed consent was obtained from all participants. We enrolled 30 patients with suspected deep venous thrombosis or pulmonary embolism who were to undergo 80-kVp CTV studies.

Development and validation of a logistic regression model to distinguish transition zone cancers from benign prostatic hyperplasia on multi-parametric prostate MRI.

Purpose: To develop a prediction model to distinguish between transition zone (TZ) cancers and benign prostatic hyperplasia (BPH) on multi-parametric prostate magnetic resonance imaging (mp-MRI).

Materials And Methods: This retrospective study enrolled 60 patients with either BPH or TZ cancer, who had undergone 3 T-MRI. We generated ten parameters for T2-weighted images (T2WI), diffusion-weighted images (DWI) and dynamic MRI.

Feasibility of Iterative Model Reconstruction for Unenhanced Lumbar CT.

Purpose To evaluate the image quality and interobserver reproducibility of unenhanced lumbar spinal computed tomography (CT) images reconstructed with iterative model reconstruction (IMR). Materials and Methods This prospective study was approved by the local ethics committee, and written informed consent was obtained from all patients. The study included 34 patients scanned with unenhanced CT and magnetic resonance (MR) imaging for lumbar canal spinal stenosis.

Multiferroics. Magnetoelectric domain control in multiferroic TbMnO₃.

The manipulation of domains by external fields in ferroic materials is of major interest for applications. In multiferroics with strongly coupled magnetic and electric order, however, the magnetoelectric coupling on the level of the domains is largely unexplored. We investigated the field-induced domain dynamics of TbMnO3 in the multiferroic ground state and across a first-order spin-flop transition.

Giant spin-driven ferroelectric polarization in TbMnO3 under high pressure.

The recent research on multiferroics has provided solid evidence that the breaking of inversion symmetry by spin order can induce ferroelectric polarization P. This type of multiferroics, called spin-driven ferroelectrics, often show a gigantic change in P on application of a magnetic field B. However, their polarization (<~0.

A cross-sectional study for glucose intolerance of myotonic dystrophy.

We made a cross-sectional study to analyze glucose intolerance of myotonic dystrophy type 1 (DM1) with several examination including oral glucose tolerance test (OGTT), insulin tolerance test (ITT) and adiponectin. Ninety-five DM1 patients participated in this study. Health examination data from general people were used as controls.

Dermoid cyst of the urinary bladder as a differential diagnosis of bladder calculus: a case report.

Dermoid cysts are extremely rare in the urinary bladder and can pose a diagnostic dilemma to both the Urologist and the Histopathologist. Only a few cases were found documented and cited in PubMed. We present a case of dermoid cyst in the urinary bladder presenting as a bladder stone with a brief review of the literature.

[A case of thymoma-associated myasthenia gravis with antibodies against interferon-alpha--a clinico-immunological follow up of the symptoms and its titer].

A 73-year-old woman developed myasthenia gravis (MG) with thymoma. She had a very high level of serum antibodies against interferon-alfa (IFN-alpha). We observed the changes to her clinical symptoms and titer of the antibody during therapeutic course.

Laparoscopic splenectomy for a giant splenic epidermoid cyst: report of a case.

The use of laparoscopic splenectomy has increased in recent years, primarily for patients with idiopathic thrombocytopenic purpura (ITP). We describe herein the first known case of a laparoscopic splenectomy to be performed in Japan for a patient with a giant splenic epidermoid cyst. A 26-year-old woman presented to our hospital with the major complaint of a feeling of abdominal fullness.

The 3-dimensional representation of EEG distance by use of Shannon-Gelfand-Yaglom information measure during mental arithmetic.

EEG relationships in delta, theta, alpha and beta frequency bands as well as the whole frequency range among 12 electrode locations during resting and mental arithmetic were examined by use of Shannon-Gelfand-Yaglom information measure (SGY) in 10 normal subjects. The EEG relationships were represented in a 3-dimensional (3-D) feature space with multidimensional scaling (MDS). MDS resulted in an anterior-posterior, a left-right and an upper-lower axis.

Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria.

We examined the intracellular distribution of 8-oxo-dGTPase (8-oxo-7,8-dihydrodeoxyguanosine triphosphatase) encoded by the MTH1 gene, a human mutator homologue. The activity of 8-oxo-dGTPase mainly located in cytosolic and mitochondrial soluble fractions of Jurkat cells, a human T-cell leukemia line. Electron microscopic immunocytochemistry, using a specific antibody against MTH1 protein, showed localization of MTH1 protein in the mitochondrial matrix.