Biophysical Modeling of the Ionizing Radiation Influence on Cells Using the Stochastic (Monte Carlo) and Deterministic (Analytical) Approaches.

This review article describes our simplified biophysical model for the response of a group of cells to ionizing radiation. The model, which is a product of 10 years of studies, acts as (a) a comprehensive stochastic approach based on the Monte Carlo simulation with a probability tree and (b) the thereof derived detailed deterministic models describing the selected biophysical and radiobiological phenomena in an analytical manner. Specifically, the presented model describes effects such as the risk of neoplastic transformation of cells relative to the absorbed radiation dose, the dynamics of tumor development, the priming dose effect (also called the Raper-Yonezawa effect) based on the introduced adaptive response approach, and the bystander effect.

Analytical and quasi-Bayesian methods as development of the iterative approach for mixed radiation biodosimetry.

The present paper proposes two methods of calculating components of the dose absorbed by the human body after exposure to a mixed neutron and gamma radiation field. The article presents a novel approach to replace the common iterative method in its analytical form, thus reducing the calculation time. It also shows a possibility of estimating the neutron and gamma doses when their ratio in a mixed beam is not precisely known.

Calibration factor fluctuation for radiological protection instruments used in Nuclear Medicine Departments - experience from CLOR.

Background: The calibration of the dosimetric instruments is a basis of safety of the people working with the ionization radiation. The necessity of calibration is especially important in the institutions where the open radioactive sources are used. The paper presents the abilities of CLOR's radiological protection instruments calibration facility and the important conclusions from calibrations results for group of instruments used in Nuclear Medicine Department in Poland.