Publications by Iwona M Hirschler-Laszkiewicz

Publications by authors named "Iwona M Hirschler-Laszkiewicz"

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The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2.

Lei Bao Fernanda Festa Christopher S Freet John P Lee Iwona M Hirschler-Laszkiewicz

Sci Rep

October 2019

Transient receptor potential melastatin channel subfamily member 2 (TRPM2) has an essential role in protecting cell viability through modulation of oxidative stress. TRPM2 is highly expressed in cancer. When TRPM2 is inhibited, mitochondria are dysfunctional, ROS levels are increased, and cell viability is reduced.

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