[Anesthetic management of a patient with hereditary spastic paraplegia].

We experienced the anesthetic management of a 39 year-old-male with hereditary spastic paraplegia (HSP) associated with pain due to pes cavus. He underwent orthomorphia ostectomy and tenodesis. Preoperative neurological examination revealed that he had slight dementia, symptoms of the pyramidal tract, lower limb bathyhypesthesia, and neurogenic bladder in addition to spastic paraplegia, and he was diagnosed as having combined type of HSP.

Effect of the lithotomy position on spinal anesthesia with hyperbaric tetracaine.

This study was performed to determine the effects of lithotomy position on the spread of analgesia and hemodynamics following spinal anesthesia with 0.5% hyperbaric tetracaine. Thirty patients who underwent hysterectomy due to myoma uteri were studied.

Effects of lumbar puncture position on arterial blood gases.

We observed the changes in partial pressure of arterial oxygen (PaO ) and carbon dioxide (PaCO ) before and during assumption of the lateral position prior to lumbar puncture in 81 patients to investigate whether lung volume decreased and ventilation was suppressed. PaO significantly decreased while the patients were in the lateral position, while PaCO remained unchanged. There was a negative correlation between the change in PaO and age [change in PaO (mmHg)=-0.

Tonic 5-HT modulation of spinal dorsal horn neuron activity evoked by both noxious and non-noxious stimuli: a source of neuronal plasticity.

The influence of tonic serotonergic modulation on the responses of spinal dorsal horn neurons to natural peripheral stimulation was examined in physiologically intact, awake, drug-free cats. Systemically administered methysergide (maximum cumulative dose 2 mg/kg) caused significant changes in responses of some dorsal horn neurons to both mildly noxious and non-noxious stimulation. Individual changes provide evidence, in this model, for tonic 5-HT modulation of many aspects of sensory transmission at the level of the spinal cord.

The cardiovascular effects of naloxone administration after fentanyl anesthesia in hypercapnic patients.

Hemodynamic changes and plasma catecholamine levels after naloxone administration were studied in seventeen postoperative patients who received nitrous oxide, oxygen, and fentanyl anesthesia combined with epidural block. Group I consisted of ten postoperative hypercapnic (PaCO2 = 55.2 +/- 2.