Publications by authors named "Ivonne Gonzalez-Ramirez"
Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1-8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9.
Sandra Rodrí Guez-Martínez Norma A Sánchez-Zauco Ivonne González-Ramírez Juan C Cancino-Diaz Mario E Cancino-Diaz
Braz J Microbiol
July 2011
Article Synopsis
- Lipopolysaccharide triggers an increase in TLR-1-8 mRNA levels in corneal fibroblasts, indicating a strong immune response.
- Researchers tested other TLR ligands and found that peptidoglycan also caused similar over-expression, while muramyldipeptide, lipoteichoic acid, and polyI:C did not.
- The findings imply that corneal fibroblasts can effectively recognize and respond to key microbial components, enhancing their defense mechanisms.