Characterising the KMP-11 and HSP-70 recombinant antigens' humoral immune response profile in chagasic patients.

Background: Antigen specificity and IgG subclass could be significant in the natural history of Chagas' disease. The relationship between the different stages of human Chagas' disease and the profiles of total IgG and its subclasses were thus analysed here; they were directed against a crude T. cruzi extract and three recombinant antigens: the T.