Long-term safety and efficacy of single-port pars plana anterior vitrectomy with limbal infusion during anterior segment surgery.

Purpose: To report the safety and efficacy of single-port pars plana anterior vitrectomy.

Setting: Cincinnati Eye Institute, Cincinnati, Ohio, USA.

Design: Retrospective case series.

Radiographic evidence of prominent retro and suborbicularis oculi fat in thyroid-associated orbitopathy.

Purpose: To compare the radiological differences in retro-orbicularis oculi fat (ROOF) and suborbiculars oculi fat (SOOF) among patients with thyroid-associated orbitopathy (TAO) and normal subjects using computed tomography (CT).

Methods: A retrospective analysis of orbital CTs was performed in 39 consecutive patients, who were imaged between October 2005 and June 2009. Bilateral orbital CTs of 16 patients with a final report significant for thyroid orbitopathy and 23 normal subjects were evaluated.

Immunoproteomic analysis of potential serum biomarker candidates in human glaucoma.

Purpose: Evidence supporting the immune system involvement in glaucoma includes increased titers of serum antibodies to retina and optic nerve proteins, although their pathogenic importance remains unclear. This study using an antibody-based proteomics approach aimed to identify disease-related antigens as candidate biomarkers of glaucoma.

Methods: Serum samples were collected from 111 patients with primary open-angle glaucoma and an age-matched control group of 49 healthy subjects without glaucoma.

Confocal microscopy of central toxic keratopathy.

Purpose: To examine the confocal microscopic findings in a case of late-onset central toxic keratopathy.

Methods: A 46-year-old man with central toxic keratopathy 2 months after IntraLASIK underwent confocal microscopy to examine the cellular findings within the flap interface.

Results: The confocal microscopy in central toxic keratopathy reveals activated keratocytes without aggregation of inflammatory cells.

Modified frontalis suspension technique with review of large series.

Purpose: To describe and report results of a modified frontalis suspension technique utilizing direct fixation to tarsus, lash margin rotation, eyelid crease fixation, conservative blepharoplasty, and rhomboidal configuration.

Methods: A retrospective chart review of frontalis suspension patients over a 28-year period was performed.

Results: Data from 171 eyelids in 93 patients were reviewed.

Biomechanical effects of intraocular pressure elevation on optic nerve/lamina cribrosa before and after peripapillary scleral collagen cross-linking.

Purpose: To evaluate the biomechanical effect of intraocular pressure (IOP) elevation on the optic nerve/lamina cribrosa complex (ON/LC) and peripapillary sclera (PS) of porcine eyes before and after localized collagen cross-linking.

Methods: Eighteen porcine globes were divided evenly into three groups. The optic nerves were transected to expose the ON/LC, and each globe was infused through an in-line pressure transducer for direct IOP control.

Rainbow glare as an optical side effect of IntraLASIK.

Purpose: To report a new optical side effect associated with the IntraLASIK procedure.

Design: Retrospective chart review and questionnaire of all patients treated with IntraLASIK from June 2004 to August 2005.

Participants: A cohort of 585 eyes (312 patients) was divided sequentially into those treated with the older-model IntraLase laser (group 1: 399 eyes of 215 patients) and those treated with the newer model (group 2: 186 eyes of 97 patients).