Endometriosis fertility index predicts pregnancy in women operated on for moderate and severe symptomatic endometriosis.

Endometriosis Fertility Index (EFI) is a clinical staging system created to predict spontaneous pregnancy outcomes in patients with endometriosis. The present study aimed at evaluating the performance of EFI in symptomatic patients, submitted to laparoscopy for moderate and severe endometriosis associated to infertility in a Brazilian population. Seventy-seven women with endometriosis and pelvic pain, who desired to become pregnant, were selected from a tertiary care unit between those operated on between May 2007 and March 2017.

Immunolocalization of stem/progenitor cell biomarkers Oct-4, C-kit and Musashi-1 in endometriotic lesions.

Background: Human endometrium harbors stem/progenitor cells (SPCs) that may contribute to the establishment of endometriosis when seeded outside the uterus. Oct-4, C-kit and Musashi-1 are some of the many proteins used to characterize SPCs, but their association with endometriosis is uncertain.

Objective And Design: In this study, specimens of normal endometrium (n = 12), eutopic endometrium from women with endometriosis (n = 9), superficial peritoneal endometriosis (SUP, n = 12) and deep endometriosis (DE, n = 13) lesions were evaluated for localization and intensity of immunostaining for Oct-4, C-kit and Musashi-1.

Intestinal Perforation due to Deep Infiltrating Endometriosis during Pregnancy: Case Report.

We report the case of a 33 year-old woman who complained of severe dysmenorrhea since menarche. From 2003 to 2009, she underwent 4 laparoscopies for the treatment of pain associated with endometriosis. After all four interventions, the pain recurred despite the use of gonadotropin-releasing hormone (GnRH) analogues and the insertion of a levonorgestrel intrauterine system (LNG-IUS).

To operate or not to operate on women with deep infiltrating endometriosis (DIE) before in vitro fertilization (IVF).

Deep infiltrating endometriosis (DIE) can cause infertility and pelvic pain. There is little evidence of a clear connection between DIE and infertility, and the absolute benefits of surgery for DIE have not been established. This paper aimed to review the current literature on the effect of surgery for DIE on fertility, pregnancy, and IVF outcomes.

Safe multidisciplinary approach in deeply infiltrating endometriosis (DIE): is it feasible?

Objective: Evaluate the type and incidence of postoperative complications after surgery for deep infiltrative endometriosis at Biocor Hospital.

Methods: Our observational study involved a multidisciplinary surgical team that performed laparoscopy on 154 patients suffering from pelvic pain. Surgical complications occurring up to the 30th postoperative day were recorded.

A minimally invasive approach with fertility preservation in a young woman with distinct bilateral ovarian masses: a case report and review of the literature.

Adnexal masses are relatively common, contributing to gynecologist office volume and surgical case load. The development of minimally invasive techniques and a greater focus on fertility preservation have led to the favoring of a laparoscopic approach with ovarian cystectomy, when possible. We report the case of a young woman presenting with two simultaneous, distinct ovarian masses who was successfully treated by laparoscopy with preservation of both gonads.

Clinical prediction of deeply infiltrating endometriosis before surgery: is it feasible? A review of the literature.

Background: Endometriosis is a chronic benign gynecologic disease that can cause pelvic pain and infertility affecting almost 10% of reproductive-age women. Deeply infiltrating endometriosis (DIE) is a specific entity responsible for painful symptoms which are related to the anatomic location of the lesions. Definitive diagnosis requires surgery, and histological confirmation is advisable.