Publications by authors named "Iveta Vrbova"
Article Synopsis
- Aminopenicillins, like ampicillin, are recommended for treating Haemophilus influenzae infections, but resistance can develop through mutations in the ftsI gene affecting penicillin binding protein 3 (PBP3).
- The study aimed to compare how ampicillin and cefuroxime influence mutations in H. influenzae, focusing on the minimum inhibitory concentration and amino acid changes in PBP3 over time.
- Results showed cefuroxime led to a greater increase in minimum inhibitory concentration and different PBP3 mutations compared to ampicillin, indicating varying mutation selection between the two antibiotics.
The objective of this study was to assess the susceptibility of cefiderocol against multidrug-resistant carbapenemase-producing and nonproducing bacteria. The panel comprised 182 isolates of the order , and 40 strains of . Antimicrobial susceptibility testing has been performed using broth microdilution method according to the European Committee on Antimicrobial Susceptibility Testing recommendations.
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