Increased off-target binding of [18F]florbetaben in the skull of women with reduced skull density.

Aim: To investigate the relationship between off-target binding of the amyloid tracer [F]florbetaben (FBB) in the skull and skull density.

Methods: Forty-three consecutive patients were included retrospectively (age 70.2±7.

Clinical impact of whole-body 68Ga-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities.

Aim: Few small-scaled studies performed systematic analysis of the benefits of extending prostate specific membrane antigen positron-emission tomography/ computed tomography (Ga-PSMA I&T PET/CT) to the lower extremities in prostate cancer (PCa) patients. We hypothesized that Ga-PSMA I&T PET/CT positive lesions are rare in lower extremities of prostate cancer (PCa) patients, the clinical implication is negligible and may therefore be omitted.

Methods: We retrospectively analyzed 1,068 PCa patients who received Ga-PSMA I&T PET/CT in a single institution (2016-2018).