Publications by authors named "Ivana Villella"

Introducción: La Terapia de Estimulación Cognitiva (TEC) se originó en el Reino Unido. Se trata de un programa de estimulación que ha demostrado en un estudio multicéntrico, leatorizado y de diseño controlado beneficios en la cognición y la calidad de vida de los pacientes con demencia. La TEC fue adaptada e implementada en más de 30 países.

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Article Synopsis
  • The study conducted the first genome-wide association study (GWAS) on sporadic Alzheimer's disease (AD) using a sample from Argentina and Chile, involving 539 patients and 854 controls.
  • Combining their findings with data from the European Alzheimer and Dementia Biobank (EADB), researchers identified apolipoprotein E ε4 as a significant genetic risk factor and discovered four new loci linked to AD.
  • The research highlights the shared genetic factors affecting AD risk across different populations, while also noting that a genetic risk score (GRS) showed diminishing effectiveness with increasing Native American ancestry.
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