Effect of radiation on vascular endothelial growth factor expression in the C2 canine mastocytoma cell line.

Objective: To establish the radiosensitivity and effect of irradiation on vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) expression in the canine mastocytoma cell line C2.

Sample Population: Canine mastocytoma cell line C2.

Procedures: C2 cells were irradiated with single doses of 2, 4, 6, and 8 Gy.

Single-dose pharmacokinetics and genotoxicity of metronidazole in cats.

Single-dose pharmacokinetics and genotoxicity of metronidazole in cats were evaluated. Cats received either 5mg/kg metronidazole intravenously, or 20mg/kg metronidazole benzoate (12.4mg/kg metronidazole base) orally in a single dose.