Publications by authors named "Ivana M DeVengencie"
Article Synopsis
- Endothelial cells release signals that manage inflammation and restore blood vessel integrity, working alongside leukocytes and platelets to produce lipids that help resolve inflammation, such as Lipoxin A4 (LXA4).
- Aspirin, commonly used in cardiovascular conditions, inhibits the formation of proinflammatory lipids and encourages the production of anti-inflammatory mediators known as Aspirin-Triggered Lipoxins (ATL).
- The study found that cytokines increase certain signaling molecules in endothelial cells, influencing both pro-inflammatory and pro-resolving lipid production, and aspirin modulates these processes by affecting cyclooxygenase (COX) and lipoxygenase (LOX) pathways.
