Inhibition of SARS-CoV-2 M with Vitamin C, L-Arginine and a Vitamin C/L-Arginine Combination.

Background: Drug resistance is a critical problem in health care that affects therapy outcomes and requires new approaches to drug design. SARS-CoV-2 Mpro mutations are of concern as they can potentially reduce therapeutic efficacy. Viral infections are amongst the many disorders for which nutraceuticals have been employed as an adjunct therapy.