Publications by authors named "Ivan Zapolsky"

Article Synopsis
  • The study was designed as a retrospective cohort aimed at examining how overdistraction during cervical surgeries affects the subsidence of interbody cages.
  • Conducted on 68 patients who underwent anterior cervical discectomy and fusion from 2016 to 2021, the study assessed disc height at various time intervals to analyze the relationship between distraction and subsidence.
  • Results indicated that both anterior and posterior disc space subsidence were positively associated with their respective distractions, highlighting a potential risk of subsidence due to excessive distraction during surgery.
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Background Context: Clinical guidelines, developed in concordance with the literature, are often used to guide surgeons' clinical decision making. Recent advancements of large language models and artificial intelligence (AI) in the medical field come with exciting potential. OpenAI's generative AI model, known as ChatGPT, can quickly synthesize information and generate responses grounded in medical literature, which may prove to be a useful tool in clinical decision-making for spine care.

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Article Synopsis
  • The study explores the use of ChatGPT in delivering medical information by assessing its accuracy against the 2012 North American Spine Society (NASS) guidelines for lumbar disk herniation with radiculopathy.
  • ChatGPT-3.5 and ChatGPT-4 were evaluated, with ChatGPT-3.5 showing 52% accuracy and ChatGPT-4 achieving 59%, as well as a tendency for overconclusiveness in 48% and 45% of responses, respectively.
  • While results indicate potential for using ChatGPT in clinical decision-making, further research is needed to ensure safety and quality in medical care.
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Study Design: A retrospective database study of patients at an urban academic medical center undergoing an Anterior Cervical Discectomy and Fusion (ACDF) surgery between 2008 and 2019.

Objective: ACDF is one of the most common spinal procedures. Old age has been found to be a common risk factor for postoperative complications across a plethora of spine procedures.

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Purpose: Patients with adult spinal deformity (ASD) may have risk factors for nonunion and subsequent instrumentation failure. This study reviews a novel surgical technique for a quad-rod construct to the pelvis using both S2 alar iliac (S2AI) screw fixation and medialized entry iliac screw fixation as described through three separate cases and a review of the literature.

Methods: This technique facilitates alignment of the construct and rod insertion into the tulip heads.

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Article Synopsis
  • A 17-year-old boy with chronic navicular osteonecrosis underwent a complex 6-month surgery involving open reduction, internal fixation, and bone grafting to treat his condition.
  • Post-surgery, he achieved full painless weight-bearing by 4 months, with successful healing of chronic fractures and incorporation of grafts.
  • The innovative use of vascularized bone grafting allowed for preservation of the talonavicular joint, improved patient outcomes, and avoided early fusion surgery.
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The American Society for Surgery of the Hand (ASSH) was established in 1946. Since then, important advances have been made in the diagnosis and treatment of conditions affecting the upper extremity. However, there has been little documentation regarding how the largest and oldest society dedicated to hand surgery has evolved over time.

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We present a case of an adolescent patient with multiple mandibular fractures diagnosed by point-of-care ultrasound in the pediatric emergency department. Sonographic findings consistent with fracture were identified in our patient, and early consultation expedited interdepartmental coordination and disposition. The role of ultrasound in identifying various traumatic orthopedic and maxillofacial injuries is discussed.

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Zebrafish (Danio rerio) are widely used in neuroscience research, where their utility as a model organism is rapidly expanding. Low cost, ease of experimental manipulations, and sufficient behavioral complexity make zebrafish a valuable tool for high-throughput studies in biomedicine. To complement the available repositories for zebrafish genetic information, there is a growing need for the collection of zebrafish neurobehavioral and neurological phenotypes.

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Stress induced by social defeat is a strong modifier of animal anxiety and depression-like phenotypes. Self-grooming is a common rodent behavior, and has an ordered cephalo-caudal progression from licking of the paws to head, body, genitals and tail. Acute stress is known to alter grooming activity levels and disrupt its patterning.

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Article Synopsis
  • The study examines how zebrafish (Danio rerio) respond to new environments, specifically looking at their ability to habituate, or get used to new stimuli.
  • Findings show that adult zebrafish demonstrate strong habituation responses and that certain anxiogenic drugs can negatively impact this ability.
  • The research suggests that zebrafish could be a valuable model for understanding cognitive behavior and anxiety, similar to studies conducted on rodents.
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The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral neuroscience research. Zebrafish behavior is robustly affected by environmental and pharmacological manipulations, and can be examined using exploration-based paradigms, paralleled by analysis of endocrine (cortisol) stress responses. Discontinuation of various psychotropic drugs evokes withdrawal in both humans and rodents, characterized by increased anxiety.

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