Publications by authors named "Ivan Y Melnikov"
Article Synopsis
- The study focused on how mechanical properties of skeletal muscles change during periods of reduced gravity and the effect of plantar mechanical stimulation (PMS) on these properties.
- Researchers found that after a week of hindlimb suspension (HS), rats experienced a significant loss in muscle weight and strength, but PMS helped maintain maximum strength despite not preventing muscle atrophy.
- The use of a nitric oxide synthase (NOS) inhibitor reduced the benefits of PMS, indicating that the protective effects of PMS were reliant on increased nitric oxide production, which helped preserve the muscle’s passive stiffness and cytoskeletal protein levels during mechanical unloading.
