Publications by authors named "Ivan Walton"
Background: Ankle brachial pressure index can be estimated (eABPI) using cuffless ankle Doppler ultrasound. We evaluated the prognostic value of eABPI measured during pre- and post-procedural ultrasound exams to predict the clinical outcome after endovascular revascularisations.
Methods: In this prospective, single-centre, service evaluation, consecutive patients with symptomatic peripheral artery disease undergoing lower limb endovascular revascularisations between July, 26 2018 and January, 13 2022 at Surrey and Sussex Healthcare NHS Trust (Redhill, UK) were analysed.
We evaluated the impact of COVID-19 restriction on the angioplasty service and outcome of chronic limb-threatening ischaemia (CLTI) patients undergoing lower-limb angioplasty in a UK secondary care setting. Consecutive patients were analysed retrospectively. Pre-COVID-19 (08/2018-02/2020), 106 CLTI patients (91% Fontaine 4; 60% diabetes mellitus) and during COVID-19 (03/2020-07/2021) 94 patients were treated (86% Fontaine 4; 66% diabetes mellitus).
View Article and Find Full Text PDFBackground: It is well known that the global population is aging and that those over the age of 80 are the fastest growing part of this expansion. Also known is that prevalence of hypertension and cognitive decline both increase with increasing age.
Method: The Hypertension in the Very Elderly Trial (HYVET) was a double blind placebo-controlled trial of antihypertensive treatment (indapamide SR 1.
Article Synopsis
- - The Hypertension in the Very Elderly Trial (HYVET) studied the effects of antihypertensive treatment on cognitive function in elderly patients aged 80 and older, with the aim of determining if lowing blood pressure could reduce dementia risk.
- - Participants were randomly assigned to receive either antihypertensive medication (indapamide with optional perindopril) or a placebo, with cognitive function assessed annually using the mini-mental state examination (MMSE).
- - The trial found that treatment led to a significant reduction in stroke and total mortality, with very few reported adverse effects, but it did not provide definitive evidence on the impact of the treatment on dementia incidence.