Publications by authors named "Ivan Vukasinovic"

(1) Background: Laryngeal surgery due to carcinoma leads to significant tissue disruption, cellular injury, and inflammation. This leads to increased levels of reactive oxygen species (ROS), causing oxidative damage that can influence quality of life (QOL) and recovery and complicate the postoperative course. The aim of this study was to compare how postoperative quality of life and surgical complication occurrence interacted with the biomarker levels of oxidative stress (malondialdehyde, MDA; superoxide dismutase, SOD; glutathione peroxidase 1, GPX1; and catalase, CAT) and inflammation (interleukin 1, IL-1; interleukin 6, IL-6; C-reactive protein, CRP) in patients treated with conservative and radical laryngeal surgery.

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  • The report analyzes data on the treatment of peripheral artery disease (PAD) in Serbia, focusing on factors like sex differences, types of revascularization, and associated health outcomes.
  • A total of 1681 PAD patients from 27 hospitals were evaluated, revealing that men represented a larger portion of the patient group and had a higher likelihood of undergoing surgical treatments compared to women.
  • The findings underscore the significance of diabetes and smoking in PAD progression, highlighting increased risks for complications and mortality, especially in diabetic patients, while suggesting that certain treatments may lower the need for more invasive procedures like major amputations.
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  • Endovascular embolization, particularly using Menox, is shown to be a safe and effective treatment for cranial dural arteriovenous fistulas (DAVFs) in a study involving 19 patients over a two-year period.
  • Out of the patients treated, 68.4% achieved complete occlusion of their fistulas, with the highest success rates observed in certain anatomical locations.
  • Adverse events were rare, with only one intra-procedural issue noted, highlighting the overall safety of using Menox in these procedures.
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Background: Electrochemical impedance spectroscopy can determine characteristics such as cell density, size, and shape. The development of an electrical impedance-based medical device to estimate acute ischemic stroke (AIS) clot characteristics could improve stroke patient outcomes by informing clinical decision making.

Objectives: To assess how well electrical impedance combined with machine learning identified red blood cell (RBC)-rich composition of AIS clots , which is associated with a successfully modified first-pass effect.

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  • * A case study highlights the successful use of a "Stent-within-a-Stent" method for treating a giant aneurysm at the basilar artery bifurcation, followed by coil embolization.
  • * Three years post-treatment, the patient shows complete neurological recovery and is independently active and employed.
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Objectives: Atrial fibrillation (AF) is one of the leading causes of acute ischemic stroke (AIS). The aim of our study was to determine the influence of AF on the long-term outcome of patients with AIS due to anterior circulation large vessel occlusion (LVO) treated with mechanical thrombectomy (MT).

Methods: Our study included 127 consecutive patients with AIS due to anterior LVO who underwent MT between January 2018 and March 2020.

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Objectives: Mechanical thrombectomy (MT) has become leading treatment option for acute ischemic stroke (AIS) due to large vessels occlusion (LVO). Platelet counts may affect outcome in patients with AIS or transient ischemic attack. The aim of our study was to determine the influence of thrombocytopenia on the safety and efficacy of MT in patients with AIS due to anterior circulation LVO.

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  • The Thrombolysis in Ischemic Stroke Patients (TRISP) collaboration was established in 2010 to study the effectiveness and safety of intravenous thrombolysis (IVT) and has now evolved to include endovascular treatment (EVT) in a new registry called EVA-TRISP.
  • The collaboration involves 20 stroke centers committed to collecting detailed data on patients for better accuracy and investigating specific research questions regarding EVT and its outcomes.
  • The initiative aims to fill crucial gaps in knowledge about EVT's safety and effectiveness in various patient groups that may not be addressed by randomized controlled trials (RCTs), thus supporting clinical decision-making for stroke physicians.
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Stroke remains one of the leading causes of death and disability in Europe. The European Stroke Action Plan (ESAP) defines four main targets for the years 2018 to 2030. The COVID-19 pandemic forced the use of innovative technologies and created pressure to improve internet networks.

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Background and Purpose- Our goal was to evaluate whether the presence of a low signal intensity known as susceptibility vessel sign (SVS) on T2*-gradient echo imaging sequence was predictive of arterial recanalization and the early clinical improvement after mechanical thrombectomy. Methods- This observational study was based on a prospective database of acute ischemic strokes treated by mechanical thrombectomy. Inclusion criteria were patients with acute anterior ischemic stroke, diagnosed by magnetic resonance imaging, including a T2*-gradient echo imaging sequence, and treated by mechanical thrombectomy.

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Background And Purpose: Choice of anesthesia type on outcome for mechanical thrombectomy (MT) in acute ischemic stroke remains controversial. The goal of our research was to study the impact of anesthesia strategy on the delay, angiographic and neurological outcome of MT performed under general anesthesia (GA) vs. conscious sedation (CS).

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Background And Purpose: Type I and IIa dural arteriovenous fistulas (DAVFs) have a low hemorrhagic risk, but are often the cause of debilitating tinnitus that requires treatment. While Onyx® and PHIL™ (Precipitating hydrophobic injectable liquid) transarterial embolization represent the first endovascular option, there are occasional cases where performing angioplasty and stenting of the affected sinus may lead to satisfactory results.

Material And Methods: We retrospectively analyzed four consecutive cases of patients with DAVF-induced pulsatile tinnitus secondary to type I and II DAVFs who were treated with angioplasty and stenting of the sinus only.

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The incidence of concomitant extracranial carotid artery stenosis and ipsilateral intracranial carotid aneurysm has been reported to vary between 2.8% and 5%. These complex lesions may present a challenge for treatment decision-making.

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Introduction: Dural carotid cavernous fistula is acquired, relatively rare, condition comprising of numerous small-caliber meningeal arterial branches, draining directly into cavernous sinus. Endovascular therapy is the treatment of choice, preferably by a transvenous approach. In the case of inaccessible inferior petrosal sinus, other alternative routes are considered.

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