Publications by authors named "Ivan Vonke"
Article Synopsis
- The manuscript presents a review of haemophilia A treatment changes in adult patients in the Czech Republic from 2013 to 2021, highlighting data from the Czech National Haemophilia Programme.
- The study shows that switching from on-demand treatment to prophylaxis significantly reduced annual bleeding rates (ABR) and joint bleeding rates (AJBR) while increasing factor VIII consumption.
- With more patients on prophylaxis, the ABR decreased 6.9-fold and the AJBR decreased 8.7-fold, demonstrating the benefits of prophylactic treatment despite increased costs.
Rapid Progression of COVID-19-Associated Fatal Capillary Leak Syndrome.
Infect Dis Rep
November 2022
Several cases of capillary leak syndrome (CLS) related to COVID-19 or vaccination against SARS-CoV-2 have been described in the literature. We present a case of a 42-year-old, previously healthy male, presenting with a mild form of COVID-19, who suddenly developed severe shock with hypotension and severe hemoconcentration within hours of admission to the hospital. Volume resuscitation was not effective, increasing hemoglobin (198 g/L on admission, 222 g/L 9 h later) suggested fluid leak into peripheral tissues.
View Article and Find Full Text PDFIntroduction: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant condition with a risk of malignant conversion.
Patients And Methods: With the aim to estimate the cumulative risk MGUS progression to hematologic malignancies, we analyzed a nationwide population-based cohort of 1887 MGUS patients from the Czech Registry of Monoclonal Gammopathies (RMG) between 2007 and 2013.
Results: During the follow-up period (median 4 years; range 0.