Publications by authors named "Ivan Uriel Valladares-Hernandez"
Molecular cloning, functional characterization and differential expression of two novel GABAR-like subunits from red swamp crayfish Procambarus clarkii.
Iván Uriel Valladares-Hernández Juan Manuel Hernández-Martínez José Miguel Cuaxospa Eric Nahum Jiménez-Vázquez Edith Sánchez-Jaramillo
Eur J Neurosci
October 2024
Article Synopsis
- Researchers cloned and expressed two new GABA receptor subunits from crayfish, named PcGABA-α and PcGABA-β2, which are related to previously known receptors.
- Electrophysiological studies indicated that while the new subunits alone couldn’t create functional receptors, their combination produced two types of GABA receptors with distinct ion selectivity.
- Overall, these findings suggest that PcGABA-α and PcGABA-β2 are important for understanding GABA signaling in the crayfish nervous system, highlighting the existence of novel neural GABA-gated channels.