Publications by authors named "Ivan Perez-de Pedro"

The therapeutic management and short-term consequences of the coronavirus disease 2019 (COVID-19) are well known. However, COVID-19 post-acute sequelae are less known and represent a public health problem worldwide. Patients with COVID-19 who present post-acute sequelae may display immune dysregulation, a procoagulant state, and persistent microvascular endotheliopathy that could trigger microvascular thrombosis.

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Inflammatory pseudo tumor (IP) is an infrequent process with benign evolution in most cases whose etiology and pathogenesis are unknown. It usually affects young men and children, in whom the macroscopic lesion can mimic a malignant process, which is ruled out after biopsy. Therefore, the diagnosis of certainty is histological and treatment consists of corticosteroids, leaving resection for cases in which biopsy is not possible or in which it produces local complications.

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Article Synopsis
  • The study aimed to identify the prevalence of late-onset Pompe disease (LOPD) among patients in Internal Medicine departments in Spain who showed possible signs of the disease but were undiagnosed.
  • It was a multicenter, observational study that used dried blood spots (DBS) to screen for LOPD, confirming diagnosis through further enzyme activity tests and genetic testing if initial DBS results indicated low enzyme activity.
  • The findings revealed a low prevalence of LOPD, confirming the disease in only 2 out of 322 patients (0.6%), suggesting there may be a hidden population that could benefit from earlier diagnosis and treatment.
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The coronavirus disease of 2019 (COVID-19) has been a cause of significant morbidity and mortality worldwide. Among the short- and long-term consequences of COVID-19, myocarditis is a disease to be taken into consideration. Myocarditis, in general, is related to a poor prognosis.

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Obesity, diabetes mellitus, and cardiovascular risk are real challenges in systemic lupus erythematosus (SLE) clinical practice and research. The evidence of the burden of these health problems in SLE patients is determined by the methods used to assess them. Therefore, the aim of this scoping review is to map current approaches in assessing obesity, diabetes mellitus, and cardiovascular risk burden in SLE patients and to identify existing knowledge gaps in this field.

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Objective: To assess the efficacy and safety of tocilizumab (TCZ) in Caucasian patients with refractory Takayasu's arteritis (TAK) in clinical practice.

Methods: A multicenter study of Caucasian patients with refractory TAK who received TCZ. The outcome variables were remission, glucocorticoid-sparing effect, improvement in imaging techniques, and adverse events.

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(1) Objectives: To describe the clinical characteristics and clinical course of hospitalized patients with COVID-19 and autoimmune diseases (ADs) compared to the general population. (2) Methods: We used information available in the nationwide Spanish SEMI-COVID-19 Registry, which retrospectively compiles data from the first admission of adult patients with COVID-19. We selected all patients with ADs included in the registry and compared them to the remaining patients.

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We report 3 cases of left iliac vein thrombosis whose underlying cause was right iliac artery compression syndrome, also known as May-Thurner syndrome. Endovascular treatment with anatomical correction (stent placement) was applied in 2 of the cases; anticoagulant therapy was maintained given the presence of associated hypercoagulability. A thorough understanding of this diagnosis is important so that an attempt at anatomical correction can be proposed to complement anticoagulant therapy in the interest of improving prognosis.

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Introduction: Imported diseases pose a diagnostic challenge for the physician, epidemiologists, and the local health care authorities, implying a risk for the community in some cases.

Method: We report the case of a patient with Chikungunya virus infection in Spain and describe the clinical and epidemiological characteristics of this condition.

Results: Diagnosis was confirmed by specific tests in paired samples.

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Introduction: The reported prevalence of primary resistance mutations differs between studies. An analysis was performed to determine the prevalence of primary resistance mutations and HIV subtypes in our area.

Methods: Prospective study performed in all patients diagnosed with HIV in the year 2005 in the province of Malaga (Spain).

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