Publications by authors named "Ivan J Brenkel"

Introduction: This study evaluated total knee arthroplasty (TKA) outcomes for an Existing-TKA versus New-TKA from the same manufacturer.

Methods: TKA outcomes for 752 with Existing-TKA versus 1129 subjects with New-TKA were followed through 2 years using patient-reported outcome measures (PROMs). Responders were assessed per Outcome Measures in Rheumatology-Osteoarthritis Research Society International criteria.

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Introduction: The primary aim of this study was to describe a baseline comparison of early knee-specific functional outcomes following revision total knee arthroplasty (TKA) using metaphyseal sleeves with a matched cohort of patients undergoing primary TKA. The secondary aim was to compare incidence of complications and length of stay (LOS) between the two groups.

Methods: Patients undergoing revision TKA for all diagnoses between 2009 and 2016 had patient-reported outcome measures (PROMs) collected prospectively.

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Background: We report 15-year survival, clinical, and radiographic follow-up data for the Press-Fit Condylar Sigma total knee arthroplasty.

Methods: Between October 1998 and October 1999, 235 consecutive TKAs were performed in 203 patients. Patients were reviewed at a specialist nurse-led clinic before surgery and at 5, 8-10, and 15 years postoperatively.

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The aim of this study was to identify pre-operative and intra-operative factors that are predictive of dislocation following primary total hip replacement (THR). Data were prospectively collected for a consecutive series of 4334 THRs undertaken over a 14-year period. Ninety-eight (2.

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Background: Patient reported outcome measures are widely used in the evaluation of outcomes after Total Knee Replacement (TKR) in joint registries and large studies. The aim of this study was to assess the relationship between the Oxford knee score (OKS) and range of motion (ROM) after TKR, and to construct and validate prediction models of ROM from the measured OKS.

Methods: Eight hundred sixty patients reviewed five years postoperatively and 273 patients reviewed nine to 10 years postoperatively completed an OKS.

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Metaphyseal sleeve prostheses have shown promising results in the management of bone defects at revision TKA. We present a study of their use in aseptic revision TKA. Thirty-five revisions were included in 34 patients with wear or aseptic loosening indicated in 71% of cases.

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Article Synopsis
  • Total knee replacement (TKR) is increasingly common in elderly patients, but there is limited information on outcomes and complications specifically for this demographic.
  • Analyzing data from over 3,000 knee replacements, the study found that older patients (over 75) faced higher rates of complications like blood transfusion and postoperative confusion compared to younger patients, while overall improvement in knee function scores was similar across age groups.
  • The results suggest that while older adults can significantly benefit from TKR, they should be informed about potential for longer recovery times and increased medical risks associated with surgery.
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Background: Not all patients gain the same degree of improvement from total hip replacement and the reasons for this are not clear. Many investigators have assessed predictors of general outcome after hip surgery. This study is unique in its quest for the predictors of the best possible early outcome.

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National joint registries have become well established across the world. Most registries track implant survival so that poorly performing implants can be removed from the market. The Scottish Arthroplasty Project was established in 1999 with the aim of encouraging continual improvement in the quality of care provided to joint replacement patients in Scotland.

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Article Synopsis
  • The study compared the outcomes of unipolar and bipolar uncemented hemiarthroplasty in elderly patients with hip fractures.
  • Patients who had bipolar hemiarthroplasty showed better mobility and lower mortality rates compared to those with unipolar hemiarthroplasty.
  • Factors like age, gender, and pre-surgery fitness levels influenced outcomes, with bipolar hemiarthroplasty being more beneficial for patients who were physically fit before their injury.
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Early osteoarthritis (OA) is poorly understood, but abnormal chondrocyte morphology might be important. We studied IL-1β and pericellular collagen type VI in morphologically normal and abnormal chondrocytes. In situ chondrocytes within explants from nondegenerate (grade 0/1) areas of human tibial plateaus (n = 21) were fluorescently labeled and visualized [2-photon laser scanning microscopy (2PLSM)].

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Arthroscopy has been utilised in the management of knee osteoarthritis for over 70 years but in recent years there has been growing debate about the efficacy of such treatment. We reviewed data from a national register, the Scottish Arthroplasty Project. We analysed 8897 knee arthroscopies performed in patients aged over 60 in Scotland between 1997 and 2006.

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We aimed to study the effect of smoking on the complication rate and medium-term functional outcome after total hip replacement. 1767 patients undergoing a cemented THR in one hospital were followed up prospectively at 6, 18, 36, and 60 months. Harris Hip Scores, SF-36 scores and complications were recorded.

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Objective: This was an evaluation of the cost-effectiveness of oral dabigatran etexilate compared with subcutaneous low-molecular-weight heparin (enoxaparin) for the prevention of venous thromboembolism (VTE) after total knee replacement (TKR) and total hip replacement (THR) surgery from the perspective of the UK National Health Service.

Methods: Dabigatran etexilate (220 mg once daily) was compared with enoxaparin (40 mg once daily) in patients undergoing TKR (duration of prophylaxis, 6-10 days) and THR (duration of prophylaxis, 28-35 days). The 10-week acute postsurgical phase was modeled using a decision tree.

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We report a prospective study of 1509 consecutive total knee arthroplasties looking at risk factors for infection in modern surgical practice. The overall deep infection rate was 1%. A further 51 patients had a superficial infection (3.

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Six hundred twenty-two primary total knee arthroplasties were studied prospectively in 512 patients. A group with no pain and one with severe pain at 5 years were statistically compared. The following were significant predictors of poor pain outcomes: age below 60 (17%) compared with above 60 (7%, P < .

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The DePuy Sigma total knee arthroplasty (TKA) was introduced in 1997 as a modification of the Press Fit Condylar Knee (PFC) TKA and has been used extensively in the United Kingdom and worldwide. It is the most commonly used TKA in England and Wales, where it accounts for 36% of all primary TKA. The PFC was well established, with reported 10-year survival rates of 93-97%, but this study reports the first 5-year clinical and radiographic follow-up data for the Sigma TKA.

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There are few direct comparative studies evaluating results after unicompartmental knee arthroplasty and total knee arthroplasty. We determined the active range of motion, Knee Society score, and 5-year survivorship rate after 54 consecutive unilateral unicompartmental knee arthroplasties compared with a matched group of 54 unilateral total knee arthroplasties. The two groups of patients were matched for age, gender, body mass index, preoperative active range of movement, and preoperative Knee Society scores.

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Data were prospectively collected on 139 total hip arthroplasties (THAs) performed by supervised specialist registrars (residents) and 397 THAs performed by consultants. The Harris Hip Score and data on comorbidity, blood loss, transfusion requirements, re-operation, dislocation, and death were recorded. Radiologic assessment of acetabular and femoral component alignment and cementation was made using 114 trainee radiographs that were available for review at 6 months.

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